Escherichia coli. This organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E.coli is easily grown in a laboratory setting and is readily amenable to genetic manipulation making it one of the most
More...studied prokaryotic model organisms. E.coli K-12 is the most widely studied strain of E. coli and serves as a reference for this species. E. coli is also one of the most diverse microbial species, containing both pathogenic and non-pathogenic strains. Pathogenic E. coli can cause urinary tract infections, neonatal meningitis, and many, often severe, intestinal diseases. Pathogenic strains often have virulence factors encoded on extrachromosomal plasmids or within bacteriophages and distinct DNA segments termed pathogenicity islands (PAIs). PAIs are likely to have been transferred horizontally and may even have integrated into the chromosome through bacteriophage or plasmid integration or transposition. These virulence factors have often been transferred from closely related, highly pathogenic, Shigella species. Among other virulence factors, enteroinvasive E. coli share an invasion plasmid with Shigella.Reference strains from the pathogenic E. coli are the urinary tract pathogens Escherichia coli IAI39 and Escherichia coli UMN026, Escherichia coli O157:H7 str. Sakai which causes hemorrhagic colitis, Escherichia coli O83:H1 str. NRG 857C which is implicated in Crohn's Disease, and Escherichia coli O104:H4 str. 2011C-3493 which cause hemolytic uremic syndrome. Less...- MuDoGeR: Multi-Domain Genome recovery from metagenomes made easy. Rocha U, et al. Mol Ecol Resour 2024 Feb
- Analysis of In-Patient Evolution of Escherichia coli Reveals Potential Links to Relapse of Bone and Joint Infections. Thiriet-Rupert S, et al. J Infect Dis 2024 May 15
- CTX-M-15/27-positive Escherichia coli and VIM-2-producing Pseudomonas putida in free-living pigeons (Columba livia) in Tunisia. Souguir M, et al. J Glob Antimicrob Resist 2024 Mar
- In-patient evolution of a high-persister Escherichia coli strain with reduced in vivo antibiotic susceptibility. Parsons JB, et al. Proc Natl Acad Sci U S A 2024 Jan 16
- Genomic and epidemiological insight of an outbreak of carbapenemase-producing Enterobacterales in a Portuguese hospital with the emergence of the new KPC-124. Manageiro V, et al. J Infect Public Health 2024 Mar
- Genome-centric analyses of 165 metagenomes show that mobile genetic elements are crucial for the transmission of antimicrobial resistance genes to pathogens in activated sludge and wastewater. Abdulkadir N, et al. Microbiol Spectr 2024 Mar 5
- Sequential Treatment Failure With Aztreonam-Ceftazidime-Avibactam Followed by Cefiderocol Due to Preexisting and Acquired Mechanisms in a New Delhi Metallo-β-lactamase-Producing Escherichia coli Causing Fatal Bloodstream Infection. Senchyna F, et al. Clin Infect Dis 2024 Jun 14
- Molecular identification and whole genome sequence analyses of methicillin-resistant and mastitis-associated Staphylococcus aureus sequence types 6 and 2454 isolated from dairy cows. Rahman MH, et al. J Genomics 2024
- Draft genome sequences of Bacillus licheniformis strains MEZBL63 and MEZBL64 harboring the lichenysin toxin operon isolated from livestock in South Africa. El Zowalaty ME, et al. Microbiol Resour Announc 2024 Mar 12
- Emergence of tet(X4)-positive Enterobacterales in retail eggs and the widespread of IncFIA(HI1)-HI1A-HI1B(R27) plasmids carrying tet(X4). Yue C, et al. Int J Food Microbiol 2024 Apr 2
- Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices. Huang KD, et al. Cell Rep Med 2024 Mar 19
- In Silico Analysis of Shiga Toxin-Producing Escherichia coli O157:H7 Strains from Presumptive Super- and Low-Shedder Cattle. Bumunang EW, et al. Toxins (Basel) 2024 Feb 5
- Occurrence and persistence of multidrug-resistant Enterobacterales isolated from urban, industrial and surface water in Monastir, Tunisia. Ncir S, et al. Sci Total Environ 2024 May 20
- Molecular epidemiology and mechanisms of carbapenem and colistin resistance in Klebsiella and other Enterobacterales from treated wastewater in Croatia. Puljko A, et al. Environ Int 2024 Mar
- Genomic characterization of a multidrug-resistant uropathogenic Escherichia coli and evaluation of Echeveria plant extracts as antibacterials. Castañeda-Meléndrez AM, et al. AIMS Microbiol 2024
- RpoS acts as a global repressor of virulence gene expression in E. coli O104:H4 and enteroaggregative E. coli. Berger P, et al. J Infect Dis 2024 Mar 25
- Occurrence and characterization of rmtB-harbouring Salmonella and Escherichia coli isolates from a pig farm in the UK. Navickaite I, et al. J Antimicrob Chemother 2024 Jun 3
- Whole genome sequencing of uropathogenic E. coli from Ireland reveals diverse resistance mechanisms and strong correlation with phenotypic (EUCAST) susceptibility testing. Whelan S, et al. Infect Genet Evol 2024 Jul
- Sporadic clone Escherichia coli ST615 as a vector and reservoir for dissemination of crucial antimicrobial resistance genes. Carrera Páez LC, et al. Front Cell Infect Microbiol 2024
- Draft genome sequences of clinical mastitis-associated Enterococcus faecalis and Enterococcus faecium carrying multiple antimicrobial resistance genes isolated from dairy cows. Rahman MH, et al. J Glob Antimicrob Resist 2024 May 23
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Reference genomes:  
Escherichia coli str. K-12 substr. MG1655Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated |
Type
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Name
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RefSeq
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INSDC
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Size (Mb)
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GC%
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Protein
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rRNA
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tRNA
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Other RNA
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Gene
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Pseudogene
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| Chr | - | NC_000913.3 | U00096.3 | 4.64 | 50.8 | 4,298 | 22 | 86 | 99 | 4,639 | 145 | |
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Escherichia coli O157:H7 str. Sakai
Morphology: Gram:Negative, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated Phenotype: Disease:Hemorrhagic colitis
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