Genome

Enterococcus faecalis Enterococcus faecalis Lineage: Bacteria[37515]; Bacillota[6135]; Bacilli[2619]; Lactobacillales[872]; Enterococcaceae[126]; Enterococcus[69]; Enterococcus faecalis[1]

Enterococcus. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both More...Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. Other Enterococcus species such as casseliflavus and gallinarum have also been implicated in opportunistic infections. Enterococcus faecalis. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The conjugative plasmids utilize a pheromone-response system to initiate genetic transfer, spreading the plasmid throughout populations, and the mechanisms of conjugation and pheromone control are studied in their own right. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism. Less...

Summary Sequence data:  genome assemblies: 3562; sequence reads: 35  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 2.94559  median protein count: 2760  median GC%: 37.4 Publications (limited to 20 most recent records) Antibiotic Resistance Characterization and Molecular Characteristics of Enterococcus Species Isolated from Combination Probiotic Preparations in China. Jin X, et al. Foodborne Pathog Dis 2024 Jan MuDoGeR: Multi-Domain Genome recovery from metagenomes made easy. Rocha U, et al. Mol Ecol Resour 2024 Feb Plasmid-encoded toxin defence mediates mutualistic microbial interactions. Moraïs S, et al. Nat Microbiol 2024 Jan Genome-centric analyses of 165 metagenomes show that mobile genetic elements are crucial for the transmission of antimicrobial resistance genes to pathogens in activated sludge and wastewater. Abdulkadir N, et al. Microbiol Spectr 2024 Mar 5 Molecular identification and whole genome sequence analyses of methicillin-resistant and mastitis-associated Staphylococcus aureus sequence types 6 and 2454 isolated from dairy cows. Rahman MH, et al. J Genomics 2024 Draft genome sequences of Bacillus licheniformis strains MEZBL63 and MEZBL64 harboring the lichenysin toxin operon isolated from livestock in South Africa. El Zowalaty ME, et al. Microbiol Resour Announc 2024 Mar 12 Cataloging the phylogenetic diversity of human bladder bacterial isolates. Du J, et al. Genome Biol 2024 Mar 21 Epidemiology and genetic diversity of linezolid-resistant Enterococcus clinical isolates in Belgium from 2013 to 2021. Mortelé O, et al. J Glob Antimicrob Resist 2024 May 7 Draft genome sequences of clinical mastitis-associated Enterococcus faecalis and Enterococcus faecium carrying multiple antimicrobial resistance genes isolated from dairy cows. Rahman MH, et al. J Glob Antimicrob Resist 2024 May 23 Metagenome-assembled genomes indicate that antimicrobial resistance genes are highly prevalent among urban bacteria and multidrug and glycopeptide resistances are ubiquitous in most taxa. Magnúsdóttir S, et al. Front Microbiol 2023 Draft genome sequences of rare Lelliottia nimipressuralis strain MEZLN61 and two Enterobacter kobei strains MEZEK193 and MEZEK194 carrying mobile colistin resistance gene mcr-9 isolated from wastewater in South Africa. El Zowalaty ME, et al. J Glob Antimicrob Resist 2023 Jun Top-Down Genomic Surveillance Approach To Investigate the Genomic Epidemiology and Antibiotic Resistance Patterns of Enterococcus faecium Detected in Cancer Patients in Arkansas. Udaondo Z, et al. Microbiol Spectr 2023 Jun 15 Arresting microbiome development limits immune system maturation and resistance to infection in mice. Lubin JB, et al. Cell Host Microbe 2023 Apr 12 Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit. Schwartz DJ, et al. Sci Transl Med 2023 May 3 Complete Genome Sequences of 37 Bacteria from the Human Vaginal Tract. Whidbey C, et al. Microbiol Resour Announc 2023 Jun 20 Prevalence of Enterococcus spp. and the Whole-Genome Characteristics of Enterococcus faecium and Enterococcus faecalis Strains Isolated from Free-Living Birds in Poland. Kwit R, et al. Pathogens 2023 Jun 16 Draft Genome Sequences of Two Clinical Mastitis-Associated Escherichia coli Strains, of Sequence Type 101 and Novel Sequence Type 13054, Isolated from Dairy Cows in Bangladesh. Rahman MH, et al. Microbiol Resour Announc 2023 Aug 22 Genomic Landscape of Multidrug Resistance and Virulence in Enterococcus faecalis IRMC827A from a Long-Term Patient. Borgio JF, et al. Biology (Basel) 2023 Sep 29 The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping. Beresford-Jones BS, et al. Cell Host Microbe 2022 Jan 12 Mining of novel secondary metabolite biosynthetic gene clusters from acid mine drainage. Wang L, et al. Sci Data 2022 Dec 9 More...  Representative (genome information for reference and representative genomes) Reference genome:   Enterococcus faecalis EnGen0336 Submitter: Broad Institute Human Pathogen Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Un - . - 2.87 37.5 2,655 12 51 4 2,738 16 Dendrogram (based on genomic BLAST)