Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver -Spatial Transcriptomics

Citrullination modulation maintains HIF-1A stabilization to drive tumor progression

Single-cell CAR T atlas reveals type2 function in 8-year leukemia remission

UV-induced reorganization of 3D genome mediates DNA damage response [Hi-C]

A Bidirectional Non-Coding RNA Promoter Mediates Long-Range Gene Expression Regulation [4C-seq]

Genome-scale CRISPRi screen identifies pcnB repression conferring improved physiology for overproduction of free fatty acids in Escherichia coli II

Intratumoral antigen-signalling traps CD8+ T cells to confine exhaustion to the tumour site (bulk TCR-Seq)

Intratumoral antigen-signalling traps CD8+ T cells to confine exhaustion to the tumour site (scRNA-Seq)

Whole genome sequencing of mouse sarcoma clones

COMPASS complex inhibition targets the metastasis initiating cell in undifferentiated pleomorphic sarcoma

Su(Hw) interacts with Combgap to establish long-range chromatin contacts

Small-molecule-induced epigenetic rejuvenation overcomes myelinogenic barriers and stimulates myelin repair [HiChIP]

Small-molecule-induced epigenetic rejuvenation overcomes myelinogenic barriers and stimulates myelin repair

Heterochromatic 3D genome organization is directed by HP1a and H3K9-dependent and independent mechanisms [Hi-C]

Heterochromatic 3D genome organization is directed by HP1a and H3K9-dependent and independent mechanisms.

Enhanced Phase Separation Mediated Oncogenicity [HiC]

Effect of mutation at the K202 site of the HDAC8 on 3D genomic structure in HeLa cells

Effect of mutation at the K202 site of the HDAC8 on 3D genomic structure and gene expression in HeLa cells

Enhanced Phase Separation Mediated Oncogenicity [HiC IMR-90]

­­Different developmental pathways generate functionally distinct populations of natural killer cells