|
| Status |
Public on Dec 29, 2021 |
| Title |
Persistent Cryptosporidium parvum infection leads to the development of tumor microenvironment in an experimental mouse model: Results of a microarray approach |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Cryptosporidium parvum has been reported to induce digestive adenocarcinoma in a rodent model of chronic cryptosporidiosis. In the current study, the transcriptomes of C. parvum infected ileo-caecal regions of mice developing tumours were analysed to identifie potential genes involved in development of cancer
|
| |
|
| Overall design |
Whole genome microarray profiling was performed on the C. parvum infected caecum tissue at days 45 and 93 post-infection. The experimental setup consisted of total 15 mice wherein each mouse was considered as an independent experiment. (4 uninfected and 3 infected mice at day 45 post-infection ; 3 uninfected and 5 infected at 93 post-infection)
|
| |
|
| Contributor(s) |
Viscogliosi E, Certad G, Hot D, Sawant M |
| Citation(s) |
34946170 |
| Submission date |
Nov 10, 2021 |
| Last update date |
Dec 30, 2021 |
| Contact name |
David Hot |
| E-mail(s) |
david.hot@pasteur-lille.fr
|
| Organization name |
Institut Pasteur de Lille
|
| Department |
Center for Infection and Immunity of Lille
|
| Lab |
Transcriptomics and Applied Genomics
|
| Street address |
1 rue du professeur Calmette
|
| City |
Lille |
| ZIP/Postal code |
59000 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL21810 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Feature Number version] |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA779477 |
Less...
More...