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Platform GPL8300 Query DataSets for GPL8300
Status Public on Mar 16, 2009
Title [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Technology type in situ oligonucleotide
Distribution commercial
Organism Homo sapiens
Manufacturer Affymetrix
Manufacture protocol see manufacturer's web site

Based on this UniGene build and associated annotations, the HG-U95Av2 array represents approximately 10,000 full-length genes.

 
Description Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www.ncbi.nlm.nih.gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html

June 03, 2009: annotation table updated with netaffx build 28
June 08, 2012: annotation table updated with netaffx build 32
June 27, 2016: annotation table updated with netaffx build 35
 
Web link http://www.affymetrix.com/support/technical/byproduct.affx?product=hgu95
http://www.affymetrix.com/analysis/index.affx
Submission date Mar 13, 2009
Last update date Dec 13, 2018
Organization Affymetrix, Inc.
E-mail(s) geo@ncbi.nlm.nih.gov, support@affymetrix.com
Phone 888-362-2447
URL http://www.affymetrix.com/index.affx
Street address
City Santa Clara
State/province CA
ZIP/Postal code 95051
Country USA
 
Samples (6446) GSM2899, GSM3388, GSM3389, GSM3390, GSM3391, GSM3392 
Series (302)
GSE96 Large-scale analysis of the human transcriptome
GSE207 HDMTX_MP-1 pair
GSE208 HDMTX_MP-10 pair

Data table header descriptions
ID Affymetrix Probe Set ID
GB_ACC GenBank Accession Number
SPOT_ID identifies controls and TIGR accessions
Species Scientific Name The genus and species of the organism represented by the probe set.
Annotation Date The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site.
Sequence Type
Sequence Source The database from which the sequence used to design this probe set was taken.
Target Description
Representative Public ID The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used.
Gene Title Title of Gene represented by the probe set.
Gene Symbol A gene symbol, when one is available (from UniGene).
ENTREZ_GENE_ID Entrez Gene Database UID
RefSeq Transcript ID References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet.
Gene Ontology Biological Process Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Cellular Component Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Molecular Function Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".

Data table
ID GB_ACC SPOT_ID Species Scientific Name Annotation Date Sequence Type Sequence Source Target Description Representative Public ID Gene Title Gene Symbol ENTREZ_GENE_ID RefSeq Transcript ID Gene Ontology Biological Process Gene Ontology Cellular Component Gene Ontology Molecular Function
1000_at X60188 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X60188 /FEATURE=mRNA /DEFINITION=HSERK1 Human ERK1 mRNA for protein serine/threonine kinase X60188 mitogen-activated protein kinase 3 MAPK3 5595 NM_001040056 /// NM_001109891 /// NM_002746 /// XR_243293 0000165 // MAPK cascade // non-traceable author statement /// 0000165 // MAPK cascade // traceable author statement /// 0000186 // activation of MAPKK activity // traceable author statement /// 0000187 // activation of MAPK activity // traceable author statement /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032872 // regulation of stress-activated MAPK cascade // traceable author statement /// 0033129 // positive regulation of histone phosphorylation // inferred from mutant phenotype /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035066 // positive regulation of histone acetylation // inferred from mutant phenotype /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051493 // regulation of cytoskeleton organization // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070849 // response to epidermal growth factor // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0072584 // caveolin-mediated endocytosis // traceable author statement /// 0090170 // regulation of Golgi inheritance // traceable author statement /// 2000641 // regulation of early endosome to late endosome transport // traceable author statement /// 2000657 // negative regulation of apolipoprotein binding // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // traceable author statement /// 0005794 // Golgi apparatus // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005901 // caveola // traceable author statement /// 0005925 // focal adhesion // traceable author statement /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0031143 // pseudopodium // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001784 // phosphotyrosine binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004707 // MAP kinase activity // non-traceable author statement /// 0004707 // MAP kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction
1001_at X60957 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X60957 /FEATURE=cds /DEFINITION=HSTIEMR Human tie mRNA for putative receptor tyrosine kinase X60957 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 TIE1 7075 NM_001253357 /// NM_005424 /// XM_005271163 /// XM_005271164 /// XM_006710869 0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007498 // mesoderm development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0045026 // plasma membrane fusion // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation
1002_f_at X65962 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X65962 /FEATURE=cds /DEFINITION=HSCP450 H.sapiens mRNA for cytochrome P-450 X65962 cytochrome P450, family 2, subfamily C, polypeptide 19 CYP2C19 1557 NM_000769 0006805 // xenobiotic metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from mutant phenotype /// 0016098 // monoterpenoid metabolic process // inferred from direct assay /// 0017144 // drug metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0042738 // exogenous drug catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0046483 // heterocycle metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // traceable author statement 0004497 // monooxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008395 // steroid hydroxylase activity // inferred from mutant phenotype /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from direct assay /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0018675 // (S)-limonene 6-monooxygenase activity // inferred from electronic annotation /// 0018676 // (S)-limonene 7-monooxygenase activity // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0020037 // heme binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052741 // (R)-limonene 6-monooxygenase activity // inferred from electronic annotation
1003_s_at X68149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X68149 /FEATURE=cds /DEFINITION=HSBLR1A Homo sapiens BLR1 gene for Burkitt's lymphoma receptor 1 X68149 chemokine (C-X-C motif) receptor 5 CXCR5 643 NM_001716 /// NM_032966 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0042113 // B cell activation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation
1004_at X68149 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X68149 /FEATURE=exon#2 /DEFINITION=HSBLR1A Homo sapiens BLR1 gene for Burkitt's lymphoma receptor 1 X68149 chemokine (C-X-C motif) receptor 5 CXCR5 643 NM_001716 /// NM_032966 0006928 // cellular component movement // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0042113 // B cell activation // inferred from electronic annotation /// 0048535 // lymph node development // inferred from electronic annotation /// 0070098 // chemokine-mediated signaling pathway // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004950 // chemokine receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016494 // C-X-C chemokine receptor activity // inferred from electronic annotation
1005_at X68277 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X68277 /FEATURE=cds /DEFINITION=HSCL100 H.sapiens CL 100 mRNA for protein tyrosine phosphatase X68277 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0000188 // inactivation of MAPK activity // inferred from sequence or structural similarity /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033574 // response to testosterone // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035970 // peptidyl-threonine dephosphorylation // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043409 // negative regulation of MAPK cascade // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051447 // negative regulation of meiotic cell cycle // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0090266 // regulation of mitotic cell cycle spindle assembly checkpoint // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // /// 0005737 // cytoplasm // inferred from direct assay 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from sequence or structural similarity
1006_at X07820 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank X07820 /FEATURE=cds /DEFINITION=HSSTROM2 Human mRNA for metalloproteinase stromelysin-2 X07820 matrix metallopeptidase 10 (stromelysin 2) MMP10 4319 NM_002425 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030574 // collagen catabolic process // traceable author statement 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation
1007_s_at U48705 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U48705 /FEATURE=mRNA /DEFINITION=HSU48705 Human receptor tyrosine kinase DDR gene, complete cds U48705 discoidin domain receptor tyrosine kinase 1 /// microRNA 4640 DDR1 /// MIR4640 780 100616237 NM_001202521 /// NM_001202522 /// NM_001202523 /// NM_001954 /// NM_013993 /// NM_013994 /// NR_039783 /// XM_005249385 /// XM_005249386 /// XM_005249387 /// XM_005249389 /// XM_005272873 /// XM_005272874 /// XM_005272875 /// XM_005272877 /// XM_005275027 /// XM_005275028 /// XM_005275030 /// XM_005275031 /// XM_005275162 /// XM_005275163 /// XM_005275164 /// XM_005275166 /// XM_005275457 /// XM_005275458 /// XM_005275459 /// XM_005275461 /// XM_006715185 /// XM_006715186 /// XM_006715187 /// XM_006715188 /// XM_006715189 /// XM_006715190 /// XM_006725501 /// XM_006725502 /// XM_006725503 /// XM_006725504 /// XM_006725505 /// XM_006725506 /// XM_006725714 /// XM_006725715 /// XM_006725716 /// XM_006725717 /// XM_006725718 /// XM_006725719 /// XM_006725720 /// XM_006725721 /// XM_006725722 /// XM_006725827 /// XM_006725828 /// XM_006725829 /// XM_006725830 /// XM_006725831 /// XM_006725832 /// XM_006726017 /// XM_006726018 /// XM_006726019 /// XM_006726020 /// XM_006726021 /// XM_006726022 /// XR_427836 /// XR_430858 /// XR_430938 /// XR_430974 /// XR_431015 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010715 // regulation of extracellular matrix disassembly // inferred from mutant phenotype /// 0014909 // smooth muscle cell migration // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from direct assay /// 0038063 // collagen-activated tyrosine kinase receptor signaling pathway // inferred from mutant phenotype /// 0038083 // peptidyl-tyrosine autophosphorylation // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0060444 // branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0061302 // smooth muscle cell-matrix adhesion // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0005518 // collagen binding // inferred from mutant phenotype /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0038062 // protein tyrosine kinase collagen receptor activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation
1008_f_at U50648 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U50648 /FEATURE=mRNA /DEFINITION=HSIIPKR17 Human interferon-inducible RNA-dependent protein kinase (Pkr) gene, exon 17 and complete cds U50648 eukaryotic translation initiation factor 2-alpha kinase 2 EIF2AK2 5610 NM_001135651 /// NM_001135652 /// NM_002759 0000186 // activation of MAPKK activity // inferred from mutant phenotype /// 0001819 // positive regulation of cytokine production // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009615 // response to virus // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay /// 0017148 // negative regulation of translation // inferred from mutant phenotype /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // traceable author statement /// 0019054 // modulation by virus of host process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0030683 // evasion or tolerance by virus of host immune response // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from sequence or structural similarity /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from sequence or structural similarity /// 0033689 // negative regulation of osteoblast proliferation // inferred from mutant phenotype /// 0035455 // response to interferon-alpha // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // inferred from electronic annotation /// 1900225 // regulation of NLRP3 inflammasome complex assembly // inferred from sequence or structural similarity /// 1901224 // positive regulation of NIK/NF-kappaB signaling // inferred from sequence or structural similarity /// 1901532 // regulation of hematopoietic progenitor cell differentiation // inferred from sequence or structural similarity /// 1902033 // regulation of hematopoietic stem cell proliferation // inferred from sequence or structural similarity /// 1902036 // regulation of hematopoietic stem cell differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from mutant phenotype /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004694 // eukaryotic translation initiation factor 2alpha kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay
1009_at U51004 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U51004 /FEATURE= /DEFINITION=HSU51004 Homo sapiens protein kinase C inhibitor (PKCI-1) mRNA, complete cds U51004 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 /// NR_073488 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009154 // purine ribonucleotide catabolic process // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from mutant phenotype 0000118 // histone deacetylase complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from direct assay
100_g_at Y08200 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank Y08200 /FEATURE= /DEFINITION=HSRABGTRA Homo sapiens mRNA for rab geranylgeranyl transferase, alpha-subunit Y08200 Rab geranylgeranyltransferase, alpha subunit RABGGTA 5875 NM_004581 /// NM_182836 /// XM_005267959 /// XM_005267960 0006464 // cellular protein modification process // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0018342 // protein prenylation // inferred from electronic annotation /// 0018344 // protein geranylgeranylation // inferred from sequence or structural similarity 0005968 // Rab-protein geranylgeranyltransferase complex // inferred from sequence or structural similarity 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004663 // Rab geranylgeranyltransferase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017137 // Rab GTPase binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation
1010_at U53442 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U53442 /FEATURE= /DEFINITION=HSU53442 Human p38Beta MAP kinase mRNA, complete cds U53442 mitogen-activated protein kinase 11 MAPK11 5600 NM_002751 /// NR_110887 0000165 // MAPK cascade // inferred from electronic annotation /// 0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004707 // MAP kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation
1011_s_at U54778 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U54778 /FEATURE= /DEFINITION=HSU54778 Human 14-3-3 epsilon mRNA, complete cds U54778 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon YWHAE 7531 NM_006761 /// NR_024058 /// XM_005256784 /// XM_006725298 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0001764 // neuron migration // inferred from electronic annotation /// 0003064 // regulation of heart rate by hormone // non-traceable author statement /// 0006605 // protein targeting // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0035308 // negative regulation of protein dephosphorylation // inferred from electronic annotation /// 0035329 // hippo signaling // traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0043281 // regulation of cysteine-type endopeptidase activity involved in apoptotic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0061024 // membrane organization // traceable author statement /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred by curator /// 0086091 // regulation of heart rate by cardiac conduction // inferred by curator /// 0097190 // apoptotic signaling pathway // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 1902309 // negative regulation of peptidyl-serine dephosphorylation // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005871 // kinesin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0050815 // phosphoserine binding // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from physical interaction
1012_at U57317 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U57317 /FEATURE= /DEFINITION=HSU57317 Homo sapiens p300/CBP-associated factor (P/CAF) mRNA, complete cds U57317 K(lysine) acetyltransferase 2B KAT2B 8850 NM_003884 /// XM_005265528 /// XR_245162 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006360 // transcription from RNA polymerase I promoter // traceable author statement /// 0006361 // transcription initiation from RNA polymerase I promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006473 // protein acetylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007219 // Notch signaling pathway // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0010835 // regulation of protein ADP-ribosylation // inferred from direct assay /// 0016032 // viral process // inferred from electronic annotation /// 0016573 // histone acetylation // inferred from electronic annotation /// 0018076 // N-terminal peptidyl-lysine acetylation // inferred from direct assay /// 0018393 // internal peptidyl-lysine acetylation // inferred from direct assay /// 0018394 // peptidyl-lysine acetylation // inferred from direct assay /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from direct assay /// 0043966 // histone H3 acetylation // inferred from direct assay /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation 0000123 // histone acetyltransferase complex // inferred from electronic annotation /// 0000125 // PCAF complex // non-traceable author statement /// 0000776 // kinetochore // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005671 // Ada2/Gcn5/Ada3 transcription activator complex // inferred from direct assay /// 0031672 // A band // inferred from electronic annotation /// 0031674 // I band // inferred from electronic annotation /// 0042641 // actomyosin // inferred from electronic annotation 0003712 // transcription cofactor activity // inferred from physical interaction /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0004402 // histone acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from direct assay /// 0004468 // lysine N-acetyltransferase activity // inferred from sequence or structural similarity /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008080 // N-acetyltransferase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016407 // acetyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0032403 // protein complex binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction
1013_at U59913 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U59913 /FEATURE= /DEFINITION=HSU59913 Human chromosome 5 Mad homolog Smad5 mRNA, complete cds U59913 SMAD family member 5 SMAD5 4090 NM_001001419 /// NM_001001420 /// NM_005903 0001503 // ossification // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // non-traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // traceable author statement /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0043234 // protein complex // inferred from direct assay 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation
1014_at U60325 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U60325 /FEATURE= /DEFINITION=HSU60325 Human DNA polymerase gamma mRNA, nuclear gene encoding mitochondrial protein, complete cds U60325 polymerase (DNA directed), gamma POLG 5428 NM_001126131 /// NM_002693 0006259 // DNA metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006264 // mitochondrial DNA replication // inferred from electronic annotation /// 0006287 // base-excision repair, gap-filling // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005760 // gamma DNA polymerase complex // inferred from electronic annotation /// 0042645 // mitochondrial nucleoid // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0002020 // protease binding // inferred from physical interaction /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003887 // DNA-directed DNA polymerase activity // inferred from direct assay /// 0004527 // exonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation
1015_s_at U62293 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U62293 /FEATURE=mRNA /DEFINITION=HSU62293 Human LIM-kinase1 and alternatively spliced LIM-kinase1 (LIMK1) gene, complete cds U62293 LIM domain kinase 1 LIMK1 3984 NM_001204426 /// NM_002314 /// NM_016735 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0032233 // positive regulation of actin filament bundle assembly // inferred from direct assay /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from sequence or structural similarity /// 0051444 // negative regulation of ubiquitin-protein transferase activity // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation
1016_s_at U70981 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U70981 /FEATURE= /DEFINITION=HSU70981 Human interleukin-13 receptor mRNA, complete cds U70981 interleukin 13 receptor, alpha 2 IL13RA2 3598 NM_000640 0007165 // signal transduction // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement 0005615 // extracellular space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0004896 // cytokine receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation
1017_at U73737 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U73737 /FEATURE=mRNA /DEFINITION=HUMMSH06 Human hMSH6 gene, exons 6-10 and complete cds U73737 mutS homolog 6 MSH6 2956 NM_000179 /// NM_001281492 /// NM_001281493 /// NM_001281494 /// XM_005264271 0000710 // meiotic mismatch repair // not recorded /// 0000710 // meiotic mismatch repair // inferred from sequence or structural similarity /// 0006200 // ATP catabolic process // not recorded /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006281 // DNA repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from direct assay /// 0006298 // mismatch repair // inferred from genetic interaction /// 0006298 // mismatch repair // inferred from mutant phenotype /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // not recorded /// 0008340 // determination of adult lifespan // inferred from sequence or structural similarity /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from sequence or structural similarity /// 0009411 // response to UV // not recorded /// 0009411 // response to UV // inferred from sequence or structural similarity /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016446 // somatic hypermutation of immunoglobulin genes // inferred from sequence or structural similarity /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from sequence or structural similarity /// 0043570 // maintenance of DNA repeat elements // inferred from mutant phenotype /// 0045190 // isotype switching // not recorded /// 0045190 // isotype switching // inferred from sequence or structural similarity /// 0045910 // negative regulation of DNA recombination // inferred from direct assay /// 0051096 // positive regulation of helicase activity // inferred from direct assay /// 0097193 // intrinsic apoptotic signaling pathway // inferred from sequence or structural similarity 0000228 // nuclear chromosome // not recorded /// 0000790 // nuclear chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0032301 // MutSalpha complex // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000400 // four-way junction DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008094 // DNA-dependent ATPase activity // not recorded /// 0016887 // ATPase activity // inferred from direct assay /// 0030983 // mismatched DNA binding // inferred from direct assay /// 0032137 // guanine/thymine mispair binding // inferred from direct assay /// 0032142 // single guanine insertion binding // inferred from direct assay /// 0032143 // single thymine insertion binding // inferred from direct assay /// 0032357 // oxidized purine DNA binding // inferred from direct assay /// 0032405 // MutLalpha complex binding // inferred from direct assay /// 0035064 // methylated histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043531 // ADP binding // inferred from direct assay
1018_at U81787 Homo sapiens Oct 6, 2014 Exemplar sequence GenBank U81787 /FEATURE= /DEFINITION=HSU81787 Human Wnt10B mRNA, complete cds U81787 wingless-type MMTV integration site family, member 10B WNT10B 7480 NM_003394 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from expression pattern /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0014835 // myoblast differentiation involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from mutant phenotype /// 0030182 // neuron differentiation // not recorded /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from electronic annotation /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0032434 // regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0043403 // skeletal muscle tissue regeneration // inferred from electronic annotation /// 0045165 // cell fate commitment // not recorded /// 0045598 // regulation of fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045778 // positive regulation of ossification // inferred from electronic annotation /// 0045899 // positive regulation of RNA polymerase II transcriptional preinitiation complex assembly // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048641 // regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // inferred from direct assay /// 0050909 // sensory perception of taste // inferred from electronic annotation /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051885 // positive regulation of anagen // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0061196 // fungiform papilla development // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071374 // cellular response to parathyroid hormone stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // inferred from direct assay /// 0071464 // cellular response to hydrostatic pressure // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement 0005102 // receptor binding // inferred from electronic annotation /// 0005109 // frizzled binding // not recorded /// 0048018 // receptor agonist activity // inferred by curator

Total number of rows: 12625

Table truncated, full table size 27109 Kbytes.






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