The RG-U34 set includes 3 arrays with a total of 26379 entries and was indexed 29-Jan-2002. The set includes ~7,000 known genes and >17,000 EST clusters. The A array contains probes derived from all full-length or annotated genes as well as thousands of EST clusters. The B and C arrays contain only EST clusters.
June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35
The genus and species of the organism represented by the probe set.
Annotation Date
The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site.
Sequence Type
Sequence Source
The database from which the sequence used to design this probe set was taken.
Target Description
Representative Public ID
The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used.
Gene Title
Title of Gene represented by the probe set.
Gene Symbol
A gene symbol, when one is available (from UniGene).
ENTREZ_GENE_ID
Entrez Gene Database UID
RefSeq Transcript ID
References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet.
Gene Ontology Biological Process
Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Cellular Component
Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
Gene Ontology Molecular Function
Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended".
0006108 // malate metabolic process // inferred from direct assay /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay
0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay
0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0016298 // lipase activity // traceable author statement /// 0016615 // malate dehydrogenase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation
0006508 // proteolysis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from expression pattern /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007596 // blood coagulation // not recorded /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // not recorded /// 0009314 // response to radiation // inferred from expression pattern /// 0009611 // response to wounding // not recorded /// 0010466 // negative regulation of peptidase activity // not recorded /// 0010544 // negative regulation of platelet activation // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // not recorded /// 0010757 // negative regulation of plasminogen activation // inferred from electronic annotation /// 0010757 // negative regulation of plasminogen activation // not recorded /// 0010766 // negative regulation of sodium ion transport // inferred from electronic annotation /// 0010766 // negative regulation of sodium ion transport // not recorded /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from direct assay /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // inferred from electronic annotation /// 0014067 // negative regulation of phosphatidylinositol 3-kinase signaling // not recorded /// 0021683 // cerebellar granular layer morphogenesis // inferred from electronic annotation /// 0021683 // cerebellar granular layer morphogenesis // not recorded /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // not recorded /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // not recorded /// 0032940 // secretion by cell // inferred from electronic annotation /// 0032940 // secretion by cell // not recorded /// 0033363 // secretory granule organization // inferred from direct assay /// 0033363 // secretory granule organization // inferred from electronic annotation /// 0033363 // secretory granule organization // not recorded /// 0042177 // negative regulation of protein catabolic process // inferred from electronic annotation /// 0042177 // negative regulation of protein catabolic process // not recorded /// 0042628 // mating plug formation // inferred from electronic annotation /// 0042628 // mating plug formation // not recorded /// 0045861 // negative regulation of proteolysis // inferred from direct assay /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045861 // negative regulation of proteolysis // not recorded /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // not recorded /// 0048505 // regulation of timing of cell differentiation // inferred from electronic annotation /// 0048505 // regulation of timing of cell differentiation // not recorded /// 0048711 // positive regulation of astrocyte differentiation // inferred from electronic annotation /// 0048711 // positive regulation of astrocyte differentiation // not recorded /// 0050974 // detection of mechanical stimulus involved in sensory perception // inferred from electronic annotation /// 0050974 // detection of mechanical stimulus involved in sensory perception // not recorded /// 0051966 // regulation of synaptic transmission, glutamatergic // inferred from electronic annotation /// 0051966 // regulation of synaptic transmission, glutamatergic // not recorded /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // not recorded /// 0060384 // innervation // inferred from electronic annotation /// 0060384 // innervation // not recorded /// 0061108 // seminal vesicle epithelium development // inferred from electronic annotation /// 0061108 // seminal vesicle epithelium development // not recorded /// 0061110 // dense core granule biogenesis // inferred from direct assay /// 0090331 // negative regulation of platelet aggregation // inferred from electronic annotation /// 0090331 // negative regulation of platelet aggregation // not recorded
0005576 // extracellular region // not recorded /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005623 // cell // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // not recorded /// 0031091 // platelet alpha granule // inferred from electronic annotation /// 0031091 // platelet alpha granule // not recorded /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0031232 // extrinsic component of external side of plasma membrane // not recorded /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0031594 // neuromuscular junction // not recorded /// 0043025 // neuronal cell body // inferred from direct assay
0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // not recorded /// 0004867 // serine-type endopeptidase inhibitor activity // traceable author statement /// 0005102 // receptor binding // inferred from electronic annotation /// 0005102 // receptor binding // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // not recorded /// 0008201 // heparin binding // inferred from direct assay /// 0008201 // heparin binding // inferred from electronic annotation /// 0008201 // heparin binding // not recorded /// 0008233 // peptidase activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation
0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from direct assay /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from direct assay /// 0015992 // proton transport // not recorded /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0044253 // positive regulation of multicellular organismal metabolic process // traceable author statement /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0055085 // transmembrane transport // not recorded
0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // not recorded /// 0005740 // mitochondrial envelope // not recorded /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation
0017077 // oxidative phosphorylation uncoupler activity // inferred from direct assay /// 0017077 // oxidative phosphorylation uncoupler activity // not recorded
0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0048585 // negative regulation of response to stimulus // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from direct assay
0005576 // extracellular region // inferred from direct assay
0004866 // endopeptidase inhibitor activity // inferred from direct assay /// 0005179 // hormone activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from direct assay
0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // inferred from expression pattern /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from expression pattern /// 0007568 // aging // inferred from expression pattern /// 0007584 // response to nutrient // inferred from expression pattern /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0010226 // response to lithium ion // inferred from expression pattern /// 0032355 // response to estradiol // inferred from expression pattern /// 0032526 // response to retinoic acid // inferred from expression pattern /// 0032870 // cellular response to hormone stimulus // inferred from expression pattern /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042104 // positive regulation of activated T cell proliferation // not recorded /// 0042104 // positive regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from expression pattern /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred by curator /// 0043567 // regulation of insulin-like growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from expression pattern /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0051384 // response to glucocorticoid // inferred from expression pattern
0005576 // extracellular region // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // not recorded /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // not recorded
0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // not recorded /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from direct assay /// 0031994 // insulin-like growth factor I binding // inferred from mutant phenotype /// 0031994 // insulin-like growth factor I binding // not recorded /// 0031995 // insulin-like growth factor II binding // inferred from direct assay /// 0031995 // insulin-like growth factor II binding // inferred from physical interaction
0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001963 // synaptic transmission, dopaminergic // inferred from mutant phenotype /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0001975 // response to amphetamine // not recorded /// 0002016 // regulation of blood volume by renin-angiotensin // inferred from electronic annotation /// 0002016 // regulation of blood volume by renin-angiotensin // not recorded /// 0002031 // G-protein coupled receptor internalization // inferred from direct assay /// 0002031 // G-protein coupled receptor internalization // not recorded /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from mutant phenotype /// 0007186 // G-protein coupled receptor signaling pathway // not recorded /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // inferred from electronic annotation /// 0007191 // adenylate cyclase-activating dopamine receptor signaling pathway // not recorded /// 0007194 // negative regulation of adenylate cyclase activity // inferred from direct assay /// 0007194 // negative regulation of adenylate cyclase activity // not recorded /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // inferred from electronic annotation /// 0007195 // adenylate cyclase-inhibiting dopamine receptor signaling pathway // not recorded /// 0007212 // dopamine receptor signaling pathway // inferred from mutant phenotype /// 0007212 // dopamine receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // not recorded /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008542 // visual learning // inferred from electronic annotation /// 0008542 // visual learning // not recorded /// 0014059 // regulation of dopamine secretion // inferred from electronic annotation /// 0014059 // regulation of dopamine secretion // not recorded /// 0019216 // regulation of lipid metabolic process // inferred from electronic annotation /// 0019216 // regulation of lipid metabolic process // not recorded /// 0030814 // regulation of cAMP metabolic process // inferred from direct assay /// 0030814 // regulation of cAMP metabolic process // not recorded /// 0032416 // negative regulation of sodium:proton antiporter activity // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // not recorded /// 0032922 // circadian regulation of gene expression // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // not recorded /// 0034776 // response to histamine // inferred from electronic annotation /// 0034776 // response to histamine // not recorded /// 0035483 // gastric emptying // inferred from mutant phenotype /// 0035815 // positive regulation of renal sodium excretion // inferred from direct assay /// 0040012 // regulation of locomotion // inferred from mutant phenotype /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // not recorded /// 0042220 // response to cocaine // not recorded /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // traceable author statement /// 0043278 // response to morphine // inferred from electronic annotation /// 0043278 // response to morphine // not recorded /// 0045187 // regulation of circadian sleep/wake cycle, sleep // inferred from mutant phenotype /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045471 // response to ethanol // not recorded /// 0045776 // negative regulation of blood pressure // inferred from electronic annotation /// 0045776 // negative regulation of blood pressure // not recorded /// 0045840 // positive regulation of mitosis // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046717 // acid secretion // inferred from direct assay /// 0048148 // behavioral response to cocaine // inferred from mutant phenotype /// 0048148 // behavioral response to cocaine // not recorded /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // not recorded /// 0050482 // arachidonic acid secretion // inferred from electronic annotation /// 0050482 // arachidonic acid secretion // not recorded /// 0050709 // negative regulation of protein secretion // inferred from electronic annotation /// 0050709 // negative regulation of protein secretion // not recorded /// 0050883 // musculoskeletal movement, spinal reflex action // inferred from electronic annotation /// 0050883 // musculoskeletal movement, spinal reflex action // not recorded /// 0051898 // negative regulation of protein kinase B signaling // inferred from electronic annotation /// 0051898 // negative regulation of protein kinase B signaling // not recorded /// 0060134 // prepulse inhibition // inferred from electronic annotation /// 0060134 // prepulse inhibition // not recorded /// 0060160 // negative regulation of dopamine receptor signaling pathway // inferred from electronic annotation /// 0060160 // negative regulation of dopamine receptor signaling pathway // not recorded /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from electronic annotation /// 0060161 // positive regulation of dopamine receptor signaling pathway // not recorded /// 0090325 // regulation of locomotion involved in locomotory behavior // inferred from mutant phenotype
0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // not recorded /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0042995 // cell projection // inferred from direct assay /// 0045177 // apical part of cell // inferred from direct assay
0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // inferred from direct assay /// 0001591 // dopamine neurotransmitter receptor activity, coupled via Gi/Go // not recorded /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004952 // dopamine neurotransmitter receptor activity // inferred from mutant phenotype /// 0004952 // dopamine neurotransmitter receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008144 // drug binding // inferred from direct assay /// 0008144 // drug binding // not recorded /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031748 // D1 dopamine receptor binding // inferred from physical interaction /// 0035240 // dopamine binding // inferred from mutant phenotype
0001558 // regulation of cell growth // inferred from direct assay /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // not recorded /// 0001955 // blood vessel maturation // inferred from expression pattern /// 0002246 // wound healing involved in inflammatory response // inferred from electronic annotation /// 0002246 // wound healing involved in inflammatory response // not recorded /// 0002906 // negative regulation of mature B cell apoptotic process // not recorded /// 0006954 // inflammatory response // inferred from expression pattern /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from mutant phenotype /// 0007155 // cell adhesion // not recorded /// 0007155 // cell adhesion // non-traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // not recorded /// 0014070 // response to organic cyclic compound // inferred from expression pattern /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // not recorded /// 0016477 // cell migration // inferred from mutant phenotype /// 0030214 // hyaluronan catabolic process // inferred from electronic annotation /// 0030214 // hyaluronan catabolic process // not recorded /// 0031175 // neuron projection development // inferred from mutant phenotype /// 0033031 // positive regulation of neutrophil apoptotic process // inferred from mutant phenotype /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // not recorded /// 0033189 // response to vitamin A // inferred from expression pattern /// 0034116 // positive regulation of heterotypic cell-cell adhesion // inferred from electronic annotation /// 0034116 // positive regulation of heterotypic cell-cell adhesion // not recorded /// 0034238 // macrophage fusion // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // not recorded /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // not recorded /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // not recorded /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // not recorded /// 0051216 // cartilage development // inferred from electronic annotation /// 0051216 // cartilage development // not recorded /// 0060442 // branching involved in prostate gland morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // not recorded /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // not recorded /// 0070487 // monocyte aggregation // inferred from electronic annotation /// 0070487 // monocyte aggregation // not recorded /// 1900625 // positive regulation of monocyte aggregation // inferred from electronic annotation /// 1900625 // positive regulation of monocyte aggregation // not recorded /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from electronic annotation /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // not recorded
0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // not recorded /// 0005886 // plasma membrane // not recorded /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // not recorded /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // not recorded /// 0016324 // apical plasma membrane // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // not recorded
0004415 // hyalurononglucosaminidase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // not recorded /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // not recorded /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from mutant phenotype /// 0005540 // hyaluronic acid binding // not recorded /// 0019901 // protein kinase binding // inferred from physical interaction /// 0019955 // cytokine binding // not recorded /// 0051219 // phosphoprotein binding // inferred from physical interaction
0001525 // angiogenesis // inferred from electronic annotation /// 0001525 // angiogenesis // not recorded /// 0001655 // urogenital system development // inferred from electronic annotation /// 0001655 // urogenital system development // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // not recorded /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // not recorded /// 0007413 // axonal fasciculation // inferred from electronic annotation /// 0007413 // axonal fasciculation // not recorded /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0016477 // cell migration // not recorded /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // not recorded /// 0022038 // corpus callosum development // inferred from electronic annotation /// 0022038 // corpus callosum development // not recorded /// 0022407 // regulation of cell-cell adhesion // inferred from electronic annotation /// 0022407 // regulation of cell-cell adhesion // not recorded /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // not recorded /// 0032314 // regulation of Rac GTPase activity // inferred from electronic annotation /// 0032314 // regulation of Rac GTPase activity // not recorded /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // not recorded /// 0043088 // regulation of Cdc42 GTPase activity // inferred from electronic annotation /// 0043088 // regulation of Cdc42 GTPase activity // not recorded /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // not recorded /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0048013 // ephrin receptor signaling pathway // not recorded /// 0048538 // thymus development // inferred from electronic annotation /// 0048538 // thymus development // not recorded /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // not recorded /// 0050770 // regulation of axonogenesis // inferred from electronic annotation /// 0050770 // regulation of axonogenesis // not recorded /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation /// 0051965 // positive regulation of synapse assembly // not recorded /// 0060021 // palate development // inferred from electronic annotation /// 0060021 // palate development // not recorded /// 0060996 // dendritic spine development // not recorded /// 0060997 // dendritic spine morphogenesis // inferred from electronic annotation /// 0060997 // dendritic spine morphogenesis // not recorded
0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation
0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // not recorded /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation
0000902 // cell morphogenesis // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0051085 // chaperone mediated protein folding requiring cofactor // inferred from electronic annotation /// 0051085 // chaperone mediated protein folding requiring cofactor // not recorded
0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // not recorded /// 0005730 // nucleolus // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // not recorded /// 0005874 // microtubule // inferred from electronic annotation /// 0005874 // microtubule // not recorded /// 0070062 // extracellular vesicular exosome // not recorded
0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // inferred from electronic annotation /// 0043014 // alpha-tubulin binding // not recorded
0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006461 // protein complex assembly // not recorded /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // not recorded /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // not recorded /// 0009636 // response to toxic substance // inferred from expression pattern /// 0009743 // response to carbohydrate // inferred from expression pattern /// 0010039 // response to iron ion // inferred from expression pattern /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0010955 // negative regulation of protein processing // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // not recorded /// 0018205 // peptidyl-lysine modification // inferred from electronic annotation /// 0018205 // peptidyl-lysine modification // not recorded /// 0030163 // protein catabolic process // not recorded /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031648 // protein destabilization // not recorded /// 0032026 // response to magnesium ion // inferred from expression pattern /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0034504 // protein localization to nucleus // not recorded /// 0042176 // regulation of protein catabolic process // not recorded /// 0042220 // response to cocaine // inferred from expression pattern /// 0042493 // response to drug // inferred from expression pattern /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043278 // response to morphine // inferred from expression pattern /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // not recorded /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0045184 // establishment of protein localization // not recorded /// 0045472 // response to ether // inferred from expression pattern /// 0045787 // positive regulation of cell cycle // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // not recorded /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // not recorded /// 0046677 // response to antibiotic // not recorded /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0070301 // cellular response to hydrogen peroxide // inferred from expression pattern /// 0071157 // negative regulation of cell cycle arrest // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // not recorded /// 0071229 // cellular response to acid // inferred from expression pattern /// 0071236 // cellular response to antibiotic // inferred from expression pattern /// 0071301 // cellular response to vitamin B1 // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from expression pattern /// 0071312 // cellular response to alkaloid // inferred from expression pattern /// 0071363 // cellular response to growth factor stimulus // inferred from expression pattern /// 0071375 // cellular response to peptide hormone stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // not recorded /// 0071494 // cellular response to UV-C // inferred from expression pattern
0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // not recorded /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016604 // nuclear body // not recorded /// 0043234 // protein complex // inferred from electronic annotation /// 0043234 // protein complex // not recorded /// 0045202 // synapse // inferred from direct assay
0002039 // p53 binding // inferred from physical interaction /// 0002039 // p53 binding // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // not recorded /// 0019899 // enzyme binding // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // not recorded /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // not recorded /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // not recorded
0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0006461 // protein complex assembly // inferred from electronic annotation /// 0006461 // protein complex assembly // not recorded /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // not recorded /// 0007089 // traversing start control point of mitotic cell cycle // inferred from electronic annotation /// 0007089 // traversing start control point of mitotic cell cycle // not recorded /// 0009636 // response to toxic substance // inferred from expression pattern /// 0009743 // response to carbohydrate // inferred from expression pattern /// 0010039 // response to iron ion // inferred from expression pattern /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010629 // negative regulation of gene expression // inferred from mutant phenotype /// 0010955 // negative regulation of protein processing // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // not recorded /// 0018205 // peptidyl-lysine modification // inferred from electronic annotation /// 0018205 // peptidyl-lysine modification // not recorded /// 0030163 // protein catabolic process // not recorded /// 0031648 // protein destabilization // inferred from electronic annotation /// 0031648 // protein destabilization // not recorded /// 0032026 // response to magnesium ion // inferred from expression pattern /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0034504 // protein localization to nucleus // not recorded /// 0042176 // regulation of protein catabolic process // not recorded /// 0042220 // response to cocaine // inferred from expression pattern /// 0042493 // response to drug // inferred from expression pattern /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0042787 // protein ubiquitination involved in ubiquitin-dependent protein catabolic process // not recorded /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043278 // response to morphine // inferred from expression pattern /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // inferred from electronic annotation /// 0043518 // negative regulation of DNA damage response, signal transduction by p53 class mediator // not recorded /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0045184 // establishment of protein localization // not recorded /// 0045472 // response to ether // inferred from expression pattern /// 0045787 // positive regulation of cell cycle // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // not recorded /// 0045931 // positive regulation of mitotic cell cycle // inferred from electronic annotation /// 0045931 // positive regulation of mitotic cell cycle // not recorded /// 0046677 // response to antibiotic // not recorded /// 0046827 // positive regulation of protein export from nucleus // inferred from mutant phenotype /// 0048545 // response to steroid hormone // inferred from expression pattern /// 0070301 // cellular response to hydrogen peroxide // inferred from expression pattern /// 0071157 // negative regulation of cell cycle arrest // inferred from electronic annotation /// 0071157 // negative regulation of cell cycle arrest // not recorded /// 0071229 // cellular response to acid // inferred from expression pattern /// 0071236 // cellular response to antibiotic // inferred from expression pattern /// 0071301 // cellular response to vitamin B1 // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from expression pattern /// 0071312 // cellular response to alkaloid // inferred from expression pattern /// 0071363 // cellular response to growth factor stimulus // inferred from expression pattern /// 0071375 // cellular response to peptide hormone stimulus // inferred from expression pattern /// 0071391 // cellular response to estrogen stimulus // inferred from expression pattern /// 0071407 // cellular response to organic cyclic compound // inferred from expression pattern /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // not recorded /// 0071494 // cellular response to UV-C // inferred from expression pattern
0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // not recorded /// 0005654 // nucleoplasm // not recorded /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // not recorded /// 0005737 // cytoplasm // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016604 // nuclear body // inferred from electronic annotation /// 0016604 // nuclear body // not recorded /// 0043234 // protein complex // inferred from electronic annotation /// 0043234 // protein complex // not recorded /// 0045202 // synapse // inferred from direct assay
0002039 // p53 binding // inferred from physical interaction /// 0002039 // p53 binding // not recorded /// 0004842 // ubiquitin-protein transferase activity // inferred from mutant phenotype /// 0004842 // ubiquitin-protein transferase activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // not recorded /// 0019899 // enzyme binding // not recorded /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // not recorded /// 0042802 // identical protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // not recorded /// 0042975 // peroxisome proliferator activated receptor binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from electronic annotation /// 0097110 // scaffold protein binding // not recorded
0005634 // nucleus // not recorded /// 0005730 // nucleolus // not recorded /// 0005739 // mitochondrion // not recorded /// 0005743 // mitochondrial inner membrane // not recorded /// 0005747 // mitochondrial respiratory chain complex I // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // not recorded
0000413 // protein peptidyl-prolyl isomerization // not recorded /// 0006457 // protein folding // inferred from electronic annotation /// 0018208 // peptidyl-proline modification // /// 0061077 // chaperone-mediated protein folding // not recorded
0005789 // endoplasmic reticulum membrane // not recorded /// 0016020 // membrane // /// 0070062 // extracellular vesicular exosome // not recorded
0003755 // peptidyl-prolyl cis-trans isomerase activity // not recorded /// 0005515 // protein binding // inferred from electronic annotation /// 0005528 // FK506 binding // not recorded /// 0016853 // isomerase activity // inferred from electronic annotation
0006979 // response to oxidative stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // not recorded /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from electronic annotation /// 0032981 // mitochondrial respiratory chain complex I assembly // not recorded /// 0055114 // oxidation-reduction process // inferred from electronic annotation
0005739 // mitochondrion // not recorded /// 0005747 // mitochondrial respiratory chain complex I // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // not recorded /// 0016020 // membrane // inferred from electronic annotation
0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0003954 // NADH dehydrogenase activity // not recorded /// 0008137 // NADH dehydrogenase (ubiquinone) activity // not recorded /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation
0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0008104 // protein localization // inferred from electronic annotation /// 0008104 // protein localization // not recorded /// 0014070 // response to organic cyclic compound // inferred from direct assay /// 0045116 // protein neddylation // inferred from direct assay /// 0045116 // protein neddylation // not recorded
0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // not recorded /// 0070062 // extracellular vesicular exosome // not recorded
0005515 // protein binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // not recorded
0006629 // lipid metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation
0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // not recorded
0004128 // cytochrome-b5 reductase activity, acting on NAD(P)H // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation
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