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| Status |
Public on Apr 29, 2018 |
| Title |
The differential expression of miRNA between murine glioma and PNET |
| Platform organism |
synthetic construct |
| Sample organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
miRNA expression analysis of mouse glioma and PNET. Glioma was developed from SVZ cells through conditional codeletion of Pten/p53 or Rb/p53; while PNET was developed by codeletion of Rb/p53.
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| Overall design |
Pten/p53 codeleted SVZ cells always developed gliomas, while Rb/p53 cells mainly gave rise to PNET, but a small amout of Rb/p53 mice developed gliomas. Three groups: Pten/p53 glioma, Rb/p53 glioma and Rb/p53 PNET; biological control: each RNA sample was from a mouse tumour, three samples in each group.
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| Contributor(s) |
Brandner S, Li N |
| Citation(s) |
29720725 |
| Submission date |
Jun 15, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Sebastian Brandner |
| E-mail(s) |
s.brandner@ucl.ac.uk
|
| Organization name |
University College London
|
| Department |
Institute of Neurology
|
| Street address |
Queen square house, UCL Institute of Neurology
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| City |
London |
| State/province |
State... |
| ZIP/Postal code |
WC1N 3BG |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL17107 |
Exiqon miRCURY LNA™ microRNA Array - hsa, mmu & rno |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA390620 |
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