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| Status |
Public on Sep 30, 2017 |
| Title |
Expression data from BeWo cells treated without or with PKA- or EPAC-selected cAMP analogs |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Cyclic AMP activates two downstream factors, protein kinase A (PKA) and exchange protein directly activated by cAMP (EPAC) and both downstream signalings induce syncytialization, cell fusion and the production of hCG and progesterone.
We used microarray to identify novel transcription factors related to syncytialization in two cAMP signaling-stimulated BeWo cells.
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| Overall design |
Human placenta choriocarcinoma cell line BeWo cells were treated without or with Epac- or PKA-selective cAMP analogs for 48 h, of which RNAs were extracted and subjected to Affymetrix microarrays.
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| Contributor(s) |
Kusama K, Bai R, Imakawa K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 15, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Kazuya Kusama |
| E-mail(s) |
akusama@mail.ecc.u-tokyo.ac.jp
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| Organization name |
The University of Tokyo
|
| Street address |
1-1-1 Yayoi, Bunkyo-ku
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| City |
Tokyo |
| ZIP/Postal code |
1138657 |
| Country |
Japan |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA390666 |
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