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| Status |
Public on Dec 31, 2020 |
| Title |
Allele-specific genome editing using the CRISPR/Cas9 system phenocopies alopecia areata symptomatic patched hair loss in mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Using CRISPR/Cas9 for allele-specific genome editing we phenocopied AA symptomatic patched hair loss in mice engineered to carry the Cchcr1 risk allele.
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| Overall design |
Fluorescent cRNA synthesis derived from eight skin RNAs was performed using Agilent’s Low RNA Input Linear Amplification kit (Agilent Technology) and subjected to DNA microarray analysis using single-color microarray-based gene-expression analysis (SurePrint G3 Mouse GE Ver 2.0, 8 x 60K, Agilent Technology). All procedures were performed according to the manufacturer’s instructions.
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| Contributor(s) |
Oka A, Ikeda S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 28, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Akira Oka |
| E-mail(s) |
oka246@is.icc.u-tokai.ac.jp
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| Phone |
463931121
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| Organization name |
Tokai university
|
| Street address |
143 Shimokasuya
|
| City |
isehara |
| State/province |
Kanagawa |
| ZIP/Postal code |
259-1193 |
| Country |
Japan |
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| Platforms (1) |
| GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA392323 |
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