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Series GSE101533 Query DataSets for GSE101533
Status Public on Jul 18, 2017
Title Deletion of 11q in neuroblastomas drives sensitivity to PARP inhibition [SNP array]
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
Summary SNP arrays were combined with next generation sequencing (NGS) to precisely define the deleted region in 17 primary 11q-loss neuroblastomas and identify allelic variants in genes relevant for neuroblastoma aetiology. We assessed PARP inhibitor olaparib in combination with other chemotherapy medications using both in vitro and in vivo models.
 
Overall design CytoScan HD arrays (Affymetrix) were performed according to the manufacturer's directions on DNA extracted from 17 neuroblastoma tumor samples and 7 neuroblastoma cell lines.
 
Contributor(s) Font de Mora J, Sanmartín E
Citation(s) 28830922
Submission date Jul 17, 2017
Last update date Jul 25, 2021
Contact name Jaime Font de Mora
E-mail(s) fontdemora@iislafe.es
Organization name Instituto de Investigación Sanitaria La Fe
Lab Cellular an Molecular Bioogy Laboratory
Street address Avenida Fernando Abril Martorell, 106; Torre A, 5-07
City Valencia
ZIP/Postal code 46026
Country Spain
 
Platforms (1)
GPL16131 [CytoScanHD_Array] Affymetrix CytoScan HD Array
Samples (24)
GSM2705752 Neuroblastoma tumor NBX_17
GSM2705753 Neuroblastoma tumor NBX_18
GSM2705754 Neuroblastoma tumor NBX_19
This SubSeries is part of SuperSeries:
GSE101990 Deletion of 11q in neuroblastomas drives sensitivity to PARP inhibition
Relations
BioProject PRJNA394738

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE101533_RAW.tar 2.6 Gb (http)(custom) TAR (of CEL, CYCHP)
Processed data provided as supplementary file

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