|
| Status |
Public on Jan 23, 2008 |
| Title |
Evidence of the role of tick subolesin in gene expression |
| Organism |
Ixodes scapularis |
| Experiment type |
Expression profiling by array
|
| Summary |
Subolesin is an evolutionary conserved protein that was recently discovered in Ixodes scapularis as a tick protective antigen and has a role in tick blood digestion, reproduction and development. In other organisms, subolesin orthologs may be involved in the control of developmental processes. Because of the profound effect of subolesin knockdown in ticks and other organisms, we hypothesized that subolesin has a role in gene expression, thus affecting multiple cellular processes. The objective of this study was to provide support for the role of subolesin in gene expression.
Keywords: time course
|
| |
|
| Overall design |
Total RNA was prepared and pooled from subolesin dsRNA- and saline-injected ticks at 6 and 9 dpi (5 and 8 days of feeding).
|
| |
|
| Contributor(s) |
Ayoubi PJ |
| Citation(s) |
18673577 |
| Submission date |
Jan 21, 2008 |
| Last update date |
Mar 19, 2012 |
| Contact name |
Patricia J Ayoubi |
| E-mail(s) |
ayoubi@okstate.edu
|
| Phone |
405-744-6209
|
| Fax |
405-744-7799
|
| URL |
http://microarray.okstate.edu
|
| Organization name |
Oklahoma State University
|
| Department |
Biochemistry and Molecular Biology
|
| Lab |
OSU Microarray Core Facility
|
| Street address |
246 NRC
|
| City |
Stillwater |
| State/province |
OK |
| ZIP/Postal code |
74078 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6394 |
OSU subolesin dsRNA injected SSH library |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA108285 |
Less...
More...