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Status |
Public on Aug 22, 2017 |
Title |
Transcriptome characterization of murine ventricular cardiomyocytes |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We collected comprehensive RNAseq data from wildtype murine ventricular cardiomyocytes. Moreover, a cardiomyocyte-specific knockout mouse model for the ion channel regulator CASK was included, since CASK can translocate to the nucleus and regulate gene expression. Knockout models for SAP97 and dystrophin, two ion channels regulators, were also investigated.
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Overall design |
Sequencing of cardiomycyte RNA from WT mice as well as CASK KO, SAP97 KO and MDX mice. Three replicated experiments were performed for CASK KO and SAP97 KO conditions, and five replicated experiments for the MDX condition.
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Contributor(s) |
Chevalier M, Vermij S, Wyler K, Keller I, Gillet L, Abriel H |
Citation(s) |
30129933 |
Submission date |
Aug 17, 2017 |
Last update date |
May 15, 2019 |
Contact name |
Jean-Sebastien ROUGIER |
E-mail(s) |
jean-sebastien.rougier@ibmm.unibe.ch
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Organization name |
University of Bern
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Department |
IBMM
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Street address |
Bühlstrasse 28
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City |
Bern |
ZIP/Postal code |
3012 |
Country |
Switzerland |
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Platforms (1) |
GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
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Samples (22)
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Relations |
BioProject |
PRJNA398669 |
SRA |
SRP115652 |