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Series GSE103856 Query DataSets for GSE103856
Status Public on Sep 14, 2018
Title Expression data from lung and spleen natural killer cells of WT and Kras mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Natural killer (NK) cells are gradually induced into a dysfunctional state, and increasingly lose their antitumor effect during lung cancer development. To gain mechanistic insights into these findings, we performed unsupervised bioinformatic analyses by microarrays.
We used microarrays to identify a pivotal molecule involved in NK cell dysfunction.
 
Overall design WT and Kras mice (6-8 weeks old) were intranasally infected with Lenti-Cre for induction of lung cancer. At Stage 3 (16 weeks after Lenti-Cre delivery), NK cells were isolated from spleens and lungs of WT and Kras mice.
 
Contributor(s) Cong J, Wei H
Citation(s) 30033198
Submission date Sep 14, 2017
Last update date Jul 25, 2021
Contact name Shu Zhu
E-mail(s) zhushu@ustc.edu.cn
Organization name University of Science and Technology of China
Street address 443 Huangshan Road, Hefei, Anhui, China
City Hefei
ZIP/Postal code 230027
Country China
 
Platforms (1)
GPL21163 Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version]
Samples (8)
GSM2784707 Kras lung NK, replicate 1
GSM2784708 Kras lung NK, replicate 2
GSM2784709 WT lung NK, replicate 1
Relations
BioProject PRJNA407302

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE103856_RAW.tar 112.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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