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Status |
Public on Apr 18, 2018 |
Title |
Altered gene-regulatory function of KDM5C by a novel mutation associated with autism and intellectual disability |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We describe a new variant in histone demethylase KDM5C in a male with autism and intellectual disability
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Overall design |
We performed RNA-Seq from primary mouse forebrain neuronal culture. Libraries were depleted for rRNA and strand-specific according to the protocol described in PMID: 25607527
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Contributor(s) |
Vallianatos CN, Iwase S |
Citation(s) |
29670509 |
NIH grant(s) |
Grant ID |
Grant title |
Affiliation |
Name |
R01 NS089896 |
Neutralizing epigenomes in neurodevelopmental disorders |
REGENTS OF THE UNIVERSITY OF MICHIGAN - ANN ARBOR |
Shigeki Iwase |
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Submission date |
Sep 27, 2017 |
Last update date |
Mar 19, 2019 |
Contact name |
Christina N Vallianatos |
Organization name |
University of Michigan
|
Department |
Human Genetics
|
Lab |
Iwase lab
|
Street address |
1241 East Catherine
|
City |
Ann Arbor |
State/province |
MI |
ZIP/Postal code |
48109 |
Country |
USA |
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Platforms (1) |
GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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Samples (4)
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Relations |
BioProject |
PRJNA412360 |
SRA |
SRP118979 |