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| Status |
Public on Oct 22, 2018 |
| Title |
Cdk4-inhibitor induces tumor regression of Bladder cancer in vivo |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Cdk4/6 inhibitors have shown to increase overall survival in hormone-positive breast tumors, but whether other solid tumors could respond to these inhibitors has not yet defined. Here we show that Palbociclib (a Cdk4/6 specific inhibitor in clinic use) treatment exerts antiproliferative effects in vivo using a bladder cancer cell lines.
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| Overall design |
Gene expression was compared between bladder cancer cell lines with the same cell lines treated with Cdk4-inhibitor (IC50)
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| Contributor(s) |
Rubio C, Martínez-Fernández M, Segovia C, Calderon FF, Dueñas M, Paramio JM |
| Citation(s) |
30242024 |
| Submission date |
Oct 20, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Monica Martinez-Fernandez |
| E-mail(s) |
monicamartinezfernandez@gmail.com
|
| Organization name |
CIEMAT
|
| Street address |
Avda Complutense 40
|
| City |
Madrid |
| ZIP/Postal code |
28040 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA415124 |
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