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| Status |
Public on Jan 22, 2018 |
| Title |
The effect of PCN on gene expression in mouse primary hepatocytes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The effect of prototypical pregnane receptor X (PXR) agonist (pregnenolone 16α-carbonitrile) PCN on hepatic gene expression was studied in mice primary hepatocytes.
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| Overall design |
The effect of pregnenolone 16α-carbonitrile (PCN) was studied in male 9-week-old C57BL/6 mouse primary hepatocytes. Cells were treated with 10 μmol/l PCN for 12 h, DMSO was used as a control. Three parallel RNA samples were pooled in both groups. DNA microarrays we used for gene expression profiling.
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| Contributor(s) |
Hakkola J, Buler M |
| Citation(s) |
29309761 |
| Submission date |
Oct 27, 2017 |
| Last update date |
Jan 27, 2018 |
| Contact name |
Jaana Rysae |
| E-mail(s) |
jaana.rysa@gmail.com
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| Organization name |
University of Eastern Finland
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| Department |
School of Pharmacy
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| Street address |
Yliopistonranta 1C
|
| City |
Kuopio |
| ZIP/Postal code |
70211 |
| Country |
Finland |
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| Platforms (1) |
| GPL9746 |
Affymetrix GeneChip Mouse Genome 430 2.0 Array (CDF: Mouse4302_Mm_ENTREZG.cdf version 12.0.0) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA416135 |
