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| Status |
Public on Nov 24, 2017 |
| Title |
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [HiC] |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
We present the high resolution HiC study of genome folding in primary cells, specifically hematopoietic stem and progenitor cells. We investigated the relationship of chromosomal contacts with other epigenetic marks, particularly DNA methylation and histone modifications which is known to be important for appropriate stem cell differentiation.
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| |
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| Overall design |
We used in situ Hi-C to probe relationship of chromosomal contacts and epigenetic modification.
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| |
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| Contributor(s) |
Jeong M, Shamim MS, Goodell MA, Aiden EL |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 20, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jianzhong Su |
| E-mail(s) |
jianzhongsu82@gmail.com
|
| Phone |
8322902241
|
| Organization name |
Baylor college of Medicine
|
| Street address |
1 Baylor Plaza
|
| City |
HOUSTON |
| State/province |
TEXAS |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE104579 |
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells |
|
| Relations |
| BioProject |
PRJNA419462 |
| SRA |
SRP125488 |
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