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| Status |
Public on Nov 29, 2017 |
| Title |
Gene expression analysis of murine pluripotent stem cells treated with myxothiazol for 12 h |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
ROS are frequently associated with deleterious effects caused by oxidative stress. Despite the harmful effects of non-specific oxidation, ROS also function as signal transduction molecules that regulate various biological processes, including stem cell proliferation and differentiation. Here we show that elevated ROS level by myxothiazol exposure makes murine P19 pluripotent stem cells more potent to differentiate in trophoblast cells, but not in neurons.
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| Overall design |
For gene expression analysis samples were extracted from P19 cells grown under normal conditions (4 independent samples) or treated with 5 nM myxothiazol for 12 h (3 independent samples).
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| Contributor(s) |
Pashkovskaia N, Gey U, Rödel G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 28, 2017 |
| Last update date |
Jan 24, 2018 |
| Contact name |
Natalia Pashkovskaia |
| E-mail(s) |
pashkovskaia.natalia@gmail.com
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| Organization name |
Technische Universität Dresden
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| Street address |
Zellescher Weg 20B
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| City |
Dresden |
| ZIP/Postal code |
01217 |
| Country |
Germany |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA420033 |
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