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| Status |
Public on Jan 13, 2018 |
| Title |
Expression data for Tcl1 tg mice compared to CD44ΔB Tcl1 tg mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Tcl1 tg mice develop a chronic lymphocytic leukemia (CLL) -like disease. To investigate the contribution of the adhesion molecule CD44 to CLL pathophysiology, we developed a CD19Cre CD44flox/flox Tcl1 tg mouse with a B cell specific CD44 deficiency (CD44ΔB Tcl1 tg).
We used the Clariom S mouse microarray from Affymetrix to investigate transcriptional differeneces between Tcl1 tg and CD44ΔB Tcl1 tg mice
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| Overall design |
CD5+/CD19+ malignant B cells isolated from splenocytes from 4 different Tcl1 tg mice and 4 different CD44ΔB Tcl1 tg were used for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Gutjahr JC, Hartmann TN |
| Citation(s) |
29352038 |
| Submission date |
Jan 12, 2018 |
| Last update date |
Feb 01, 2019 |
| Contact name |
Julia Christine Gutjahr |
| E-mail(s) |
j.gutjahr@salk.at
|
| Phone |
00435725525857
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| Organization name |
SCRI-LIMCR
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| Department |
Department of Internal Medicine III, Paracelsus Medical University
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| Lab |
Laboratory for Immunological and Molecular Cancer Research
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| Street address |
Müllner Hauptstraße 48
|
| City |
Salzburg |
| ZIP/Postal code |
5020 |
| Country |
Austria |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA429732 |
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