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Series GSE109316 Query DataSets for GSE109316
Status Public on Jan 18, 2018
Title Microarray data of benzo[a]pyrene-treated WHCO1 vs EPC-2 cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The aim of this project was to investigate the differential effects of benzo[a]pyrene (BaP) treatment on global gene transcription, comparing normal (EPC-2) and cancer (WHCO1) cell lines from the oesophagus, in order to further our understanding of the molecular mechanisms of BaP-induced development and maintenance of oesophageal squamous cell carcinoma.
 
Overall design Two cell lines (WHCO1, esophageal squamous cell carcinoma and EPC2-hTERT, telomerase-immortalized normal esophageal cell line) were used. For both cell lines total RNA was extracted from a vehicle control (Untreated) and treatment with 10 uM benzo[a]pyrene after 24 hours treatment, with biological repeat duplicate samples for each treatment. 8 samples in total
 
Contributor(s) Bick AJ
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jan 17, 2018
Last update date Feb 18, 2019
Contact name Alexis Bick
E-mail(s) bckale003@myuct.ac.za
Phone +27216505976
Organization name University of Cape Town
Department Division of Medical Biochemistry and Structural Biology
Street address Anzio Road, Observatory
City Cape Town
State/province Western Cape
ZIP/Postal code 7925
Country South Africa
 
Platforms (1)
GPL6884 Illumina HumanWG-6 v3.0 expression beadchip
Samples (8)
GSM2938748 EPC-2 cells BaP-treated 24 h rep1
GSM2938749 EPC-2 cells BaP-treated 24 h rep2
GSM2938750 EPC-2 cells vehicle control 24h rep1
Relations
BioProject PRJNA430410

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE109316_RAW.tar 24.0 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

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