 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Dec 21, 2018 |
| Title |
In vitro transcription studies used in a proof of concept whole transcriptome model predition study - HepG2 cells (4 of 4) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
HpeG2 cells were exposed in triplicate to three agrichemicals for 24hrs at 8 concentrations and a DMSO vehicle control (0.001, 0.003, 0.01, 0.03, 0.1, 0.3, 1, 3, and 10 μM plus DMSO vehicle controls). While a common set of DMSO controls was used, these CEL files were RMA normalized independently with each of the chemical treated groups. Gene expression was measured on an Affymetrix GeneTitan system. The compounds used were fenbuconazole (a.k.a FENB, CAS # 114369-43-6) a triazole fungicide, imazalil (a.k.a. IMAZ, CAS # 35554-44-0), an azole pesticide, and 2,4-dichlorophenoxyacetic acid (a.k.a. 2,4-D or 2-4-D in file names, CAS # 94-75-7), a chlorophenoxy herbicide.
|
| |
|
| Overall design |
24hr in vitro exposures in triplicate at 9 concentrations - 0.001, 0.003, 0.01, 0.03, 0.1, 0.3, 1, 3, and 10 μM plus DMSO vehicle controls
|
| |
|
| Contributor(s) |
Black MB, Haider S |
| Citation(s) |
30333746 |
| Submission date |
Jan 23, 2018 |
| Last update date |
Dec 23, 2018 |
| Contact name |
Michael B. Black |
| E-mail(s) |
mblack@scitovation.com
|
| Phone |
919-354-5223
|
| Organization name |
Scitovation, LLC.
|
| Street address |
100 Capitola Dr., Suite 106
|
| City |
Research Triangle Park |
| State/province |
North Carolina |
| ZIP/Postal code |
27713 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13158 |
[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate |
|
| Samples (90)
|
| GSM2945069 |
HepG2 common DMSO control 1, RMA normalized with FENB samples |
| GSM2945070 |
HepG2 common DMSO control 2, RMA normalized with FENB samples |
| GSM2945071 |
HepG2 common DMSO control 3, RMA normalized with FENB samples |
| GSM2945072 |
HepG2 cells, Fenbuconazole treated at 0.001uM, rep.1 |
| GSM2945073 |
HepG2 cells, Fenbuconazole treated at 0.001uM, rep.2 |
| GSM2945074 |
HepG2 cells, Fenbuconazole treated at 0.001uM, rep.3 |
| GSM2945075 |
HepG2 cells, Fenbuconazole treated at 0.003uM, rep.1 |
| GSM2945076 |
HepG2 cells, Fenbuconazole treated at 0.003uM, rep.2 |
| GSM2945077 |
HepG2 cells, Fenbuconazole treated at 0.003uM, rep.3 |
| GSM2945078 |
HepG2 cells, Fenbuconazole treated at 0.01uM, rep.1 |
| GSM2945079 |
HepG2 cells, Fenbuconazole treated at 0.01uM, rep.2 |
| GSM2945080 |
HepG2 cells, Fenbuconazole treated at 0.01uM, rep.3 |
| GSM2945081 |
HepG2 cells, Fenbuconazole treated at 0.03uM, rep.1 |
| GSM2945082 |
HepG2 cells, Fenbuconazole treated at 0.03uM, rep.2 |
| GSM2945083 |
HepG2 cells, Fenbuconazole treated at 0.03uM, rep.3 |
| GSM2945084 |
HepG2 cells, Fenbuconazole treated at 0.1uM, rep.1 |
| GSM2945085 |
HepG2 cells, Fenbuconazole treated at 0.1uM, rep.2 |
| GSM2945086 |
HepG2 cells, Fenbuconazole treated at 0.1uM, rep.3 |
| GSM2945087 |
HepG2 cells, Fenbuconazole treated at 0.3uM, rep.1 |
| GSM2945088 |
HepG2 cells, Fenbuconazole treated at 0.3uM, rep.2 |
| GSM2945089 |
HepG2 cells, Fenbuconazole treated at 0.3uM, rep.3 |
| GSM2945090 |
HepG2 cells, Fenbuconazole treated at 1uM, rep.1 |
| GSM2945091 |
HepG2 cells, Fenbuconazole treated at 1uM, rep.2 |
| GSM2945092 |
HepG2 cells, Fenbuconazole treated at 1uM, rep.3 |
| GSM2945093 |
HepG2 cells, Fenbuconazole treated at 10uM, rep.1 |
| GSM2945094 |
HepG2 cells, Fenbuconazole treated at 10uM, rep.2 |
| GSM2945095 |
HepG2 cells, Fenbuconazole treated at 10uM, rep.3 |
| GSM2945096 |
HepG2 cells, Fenbuconazole treated at 3uM, rep.1 |
| GSM2945097 |
HepG2 cells, Fenbuconazole treated at 3uM, rep.2 |
| GSM2945098 |
HepG2 cells, Fenbuconazole treated at 3uM, rep.3 |
| GSM2945099 |
HepG2 common DMSO control 1, RMA normalized with IMAZ samples |
| GSM2945100 |
HepG2 common DMSO control 2, RMA normalized with IMAZ samples |
| GSM2945101 |
HepG2 common DMSO control 3, RMA normalized with IMAZ samples |
| GSM2945102 |
HepG2 cells, Imazalil treated at 0.001uM, rep.1 |
| GSM2945103 |
HepG2 cells, Imazalil treated at 0.001uM, rep.2 |
| GSM2945104 |
HepG2 cells, Imazalil treated at 0.001uM, rep.3 |
| GSM2945105 |
HepG2 cells, Imazalil treated at 0.003uM, rep.1 |
| GSM2945106 |
HepG2 cells, Imazalil treated at 0.003uM, rep.2 |
| GSM2945107 |
HepG2 cells, Imazalil treated at 0.003uM, rep.3 |
| GSM2945108 |
HepG2 cells, Imazalil treated at 0.01uM, rep.1 |
| GSM2945109 |
HepG2 cells, Imazalil treated at 0.01uM, rep.2 |
| GSM2945110 |
HepG2 cells, Imazalil treated at 0.01uM, rep.3 |
| GSM2945111 |
HepG2 cells, Imazalil treated at 0.03uM, rep.1 |
| GSM2945112 |
HepG2 cells, Imazalil treated at 0.03uM, rep.2 |
| GSM2945113 |
HepG2 cells, Imazalil treated at 0.03uM, rep.3 |
| GSM2945114 |
HepG2 cells, Imazalil treated at 0.1uM, rep.1 |
| GSM2945115 |
HepG2 cells, Imazalil treated at 0.1uM, rep.2 |
| GSM2945116 |
HepG2 cells, Imazalil treated at 0.1uM, rep.3 |
| GSM2945117 |
HepG2 cells, Imazalil treated at 0.3uM, rep.1 |
| GSM2945118 |
HepG2 cells, Imazalil treated at 0.3uM, rep.2 |
| GSM2945119 |
HepG2 cells, Imazalil treated at 0.3uM, rep.3 |
| GSM2945120 |
HepG2 cells, Imazalil treated at 1uM, rep.1 |
| GSM2945121 |
HepG2 cells, Imazalil treated at 1uM, rep.2 |
| GSM2945122 |
HepG2 cells, Imazalil treated at 1uM, rep.3 |
| GSM2945123 |
HepG2 cells, Imazalil treated at 10uM, rep.1 |
| GSM2945124 |
HepG2 cells, Imazalil treated at 10uM, rep.2 |
| GSM2945125 |
HepG2 cells, Imazalil treated at 10uM, rep.3 |
| GSM2945126 |
HepG2 cells, Imazalil treated at 3uM, rep.1 |
| GSM2945127 |
HepG2 cells, Imazalil treated at 3uM, rep.2 |
| GSM2945128 |
HepG2 cells, Imazalil treated at 3uM, rep.3 |
| GSM2945129 |
HepG2 common DMSO control 1, RMA normalized with 2-4-D samples |
| GSM2945130 |
HepG2 common DMSO control 2, RMA normalized with 2-4-D samples |
| GSM2945131 |
HepG2 common DMSO control 3, RMA normalized with 2-4-D samples |
| GSM2945132 |
HepG2 cells, 2,4-D treated at 0.001uM, rep.1 |
| GSM2945133 |
HepG2 cells, 2,4-D treated at 0.001uM, rep.2 |
| GSM2945134 |
HepG2 cells, 2,4-D treated at 0.001uM, rep.3 |
| GSM2945135 |
HepG2 cells, 2,4-D treated at 0.003uM, rep.1 |
| GSM2945136 |
HepG2 cells, 2,4-D treated at 0.003uM, rep.2 |
| GSM2945137 |
HepG2 cells, 2,4-D treated at 0.003uM, rep.3 |
| GSM2945138 |
HepG2 cells, 2,4-D treated at 0.01uM, rep.1 |
| GSM2945139 |
HepG2 cells, 2,4-D treated at 0.01uM, rep.2 |
| GSM2945140 |
HepG2 cells, 2,4-D treated at 0.01uM, rep.3 |
| GSM2945141 |
HepG2 cells, 2,4-D treated at 0.03uM, rep.1 |
| GSM2945142 |
HepG2 cells, 2,4-D treated at 0.03uM, rep.2 |
| GSM2945143 |
HepG2 cells, 2,4-D treated at 0.03uM, rep.3 |
| GSM2945144 |
HepG2 cells, 2,4-D treated at 0.1uM, rep.1 |
| GSM2945145 |
HepG2 cells, 2,4-D treated at 0.1uM, rep.2 |
| GSM2945146 |
HepG2 cells, 2,4-D treated at 0.1uM, rep.3 |
| GSM2945147 |
HepG2 cells, 2,4-D treated at 0.3uM, rep.1 |
| GSM2945148 |
HepG2 cells, 2,4-D treated at 0.3uM, rep.2 |
| GSM2945149 |
HepG2 cells, 2,4-D treated at 0.3uM, rep.3 |
| GSM2945150 |
HepG2 cells, 2,4-D treated at 1uM, rep.1 |
| GSM2945151 |
HepG2 cells, 2,4-D treated at 1uM, rep.2 |
| GSM2945152 |
HepG2 cells, 2,4-D treated at 1uM, rep.3 |
| GSM2945153 |
HepG2 cells, 2,4-D treated at 10uM, rep.1 |
| GSM2945154 |
HepG2 cells, 2,4-D treated at 10uM, rep.2 |
| GSM2945155 |
HepG2 cells, 2,4-D treated at 10uM, rep.3 |
| GSM2945156 |
HepG2 cells, 2,4-D treated at 3uM, rep.1 |
| GSM2945157 |
HepG2 cells, 2,4-D treated at 3uM, rep.2 |
| GSM2945158 |
HepG2 cells, 2,4-D treated at 3uM, rep.3 |
|
| This SubSeries is part of SuperSeries: |
| GSE109514 |
In vitro transcription studies used in a proof of concept whole transcriptome model predition study |
|
| Relations |
| BioProject |
PRJNA431290 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE109513_RAW.tar |
180.8 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...