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Status |
Public on Jun 08, 2021 |
Title |
Whole gene expression profiling after overexpression of Evl or miR-342 in murine hematopoietic LSK cells |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Analyzing the influence of the protein-coding gene Evl or it's intronic miR-342 on hematopoietic stem and progenitor cells on gene expression level. Evl drives lymphopoiesis, whereas miR-342 deregulates myeloid signaling pathways.
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Overall design |
Total RNA obtained from murine hematopoietic primary lineage negative (lin-) Sca1+ cKit+ (LSK) cells after lentivirus-mediated overexpression of Evl or miR-342 compared to mock.
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Web link |
https://0-www-nature-com.brum.beds.ac.uk/articles/s41375-021-01267-5#Sec18
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Contributor(s) |
Herbst F, Lang TJ, Eckert ES, Wünsche P, Wurm AA, Kindinger T, Laaber K, Hemmati S, Hotz-Wagenblatt A, Zavidij O, Paruzynski A, Lu J, von Kalle C, Zenz T, Klein C, Schmidt M, Ball CR, Glimm H |
Citation(s) |
34021250 |
Submission date |
Jan 24, 2018 |
Last update date |
Jun 10, 2021 |
Contact name |
Friederike Herbst |
E-mail(s) |
friederike.herbst@nct-heidelberg.de
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Phone |
+49-6221-56-5951
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Organization name |
National Center for Tumor Diseases (NCT) & German Cancer Research Center (DKFZ)
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Street address |
INF 460
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City |
Heidelberg |
ZIP/Postal code |
69120 |
Country |
Germany |
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Platforms (1) |
GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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Samples (6)
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Relations |
BioProject |
PRJNA431454 |