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| Status |
Public on Jan 01, 2021 |
| Title |
Differentially expressed microRNAs in antigen-specific Th17 cell cultures from WT and CD69KO mice |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
To explore miRNA signature in T cells during moderate (wild type BALB/c) and severe (cd69-/- in BALB/c background) EAM development, we performed microarray experiments with OVA-specific Th17 (Th17 Ag-sp) cell skewed cultures. The comparison of miRNA profiles from Th17 Ag-sp subsets of cd69-/- and wild type mice, with severe and mild EAM respectively, revealed a number of deregulated miRNAs.
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| Overall design |
Naïve CD4+ T cells from spleen and mesenteric lymph nodes from WT or cd69-/- OTII mice were skewed for Th17 in the presence of OVA (Th17agWT / Th17agKO).
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| Contributor(s) |
Matesanz-Marin A, Martín P |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Feb 01, 2018 |
| Last update date |
Jan 02, 2021 |
| Contact name |
Manuel J Gomez |
| E-mail(s) |
mjgomezr@cnic.es
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| Organization name |
CNIC
|
| Lab |
Bioinformatics Unit
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| Street address |
Melchor Fernández Almagro, 3
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| City |
Madrid |
| State/province |
Madrid |
| ZIP/Postal code |
28029 |
| Country |
Spain |
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| Platforms (1) |
| GPL8824 |
Agilent-019119 Mouse miRNA Microarray 1.0 G4472A (miRNA ID version) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE109995 |
microRNA signature of murine CD4+ T cell subpopulations under different skewing conditions |
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| Relations |
| BioProject |
PRJNA432541 |
