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Status |
Public on Jan 01, 2019 |
Title |
The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis |
Organism |
Nematostella vectensis |
Experiment type |
Non-coding RNA profiling by high throughput sequencing
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Summary |
knockdown of HEN1 in Nematostella results in a developmental arrest. Small RNA sequencing revealed that the levels of both miRNAs and piRNAs drop dramatically in the morphant animals.
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Overall design |
Employ height throughput sequence of endogenous small RNAs
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Contributor(s) |
Modepalli V, Fridrich A, Moran Y |
Citation missing |
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Submission date |
Feb 05, 2018 |
Last update date |
Jan 02, 2019 |
Contact name |
vengamanaidu modepalli |
E-mail(s) |
vengamanaidumodepalli@gmail.com
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Organization name |
Marine Biological Association of the UK
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Department |
Cell and Molecular
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Lab |
Dr Vengamanaidu Modepalli
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Street address |
The Laboratory,Citadel Hill
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City |
Plymouth, Devon |
State/province |
--- |
ZIP/Postal code |
PL1 2PB, |
Country |
United Kingdom |
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Platforms (1) |
GPL23029 |
Illumina NextSeq 500 (Nematostella vectensis) |
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Samples (8)
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Relations |
BioProject |
PRJNA432954 |
SRA |
SRP132200 |