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Status |
Public on Feb 28, 2018 |
Title |
Expression data from ependymal cell cultures treated with MLN4924. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
We identified that Foxj1 is degraded by the ubiquitin proteasome system. Foxj1 protein is stabilized by the cullin-RING ligase inhibitor MLN4924. We evaluated global changes to ependymal cell culture gene expression profiles during MLN4924 treatment.
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Overall design |
Fully differentiated ependymal cell cultures (2 weeks old) were either treated with DMSO as a control or with 0.25 uM MLN4924 for 36 hours.
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Contributor(s) |
Abdi K, Kuo C |
Citation(s) |
29695808 |
Submission date |
Feb 27, 2018 |
Last update date |
May 28, 2019 |
Contact name |
Khadar Abdi |
E-mail(s) |
kma9@duke.edu
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Organization name |
Duke University
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Department |
DMPI
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Lab |
White & McGarrah
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Street address |
300 North Duke St.
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City |
Durham |
State/province |
NC |
ZIP/Postal code |
27701 |
Country |
USA |
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Platforms (1) |
GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
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Samples (6)
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Relations |
BioProject |
PRJNA436123 |