|
| Status |
Public on Feb 28, 2018 |
| Title |
Expression data from ependymal cell cultures treated with MLN4924. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We identified that Foxj1 is degraded by the ubiquitin proteasome system. Foxj1 protein is stabilized by the cullin-RING ligase inhibitor MLN4924.
We evaluated global changes to ependymal cell culture gene expression profiles during MLN4924 treatment.
|
| |
|
| Overall design |
Fully differentiated ependymal cell cultures (2 weeks old) were either treated with DMSO as a control or with 0.25 uM MLN4924 for 36 hours.
|
| |
|
| Contributor(s) |
Abdi K, Kuo C |
| Citation(s) |
29695808 |
| Submission date |
Feb 27, 2018 |
| Last update date |
May 28, 2019 |
| Contact name |
Khadar Abdi |
| E-mail(s) |
kma9@duke.edu
|
| Organization name |
Duke University
|
| Department |
DMPI
|
| Lab |
White & McGarrah
|
| Street address |
300 North Duke St.
|
| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27701 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA436123 |
Less...
More...