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Series GSE111743 Query DataSets for GSE111743
Status Public on Dec 18, 2018
Title The G-rich repeats in FMR1 and C9orf72 loci are hotspots for R-loop retention and for local unpairing of DNA
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Summary We finely mapped single strand DNA displacements in FMR1 and C9orf72 and RPLA13A, a non-repetitive control locus.
 
Overall design Single strand DNA displacements were mapped by locus-specific DNA deep-sequencing following bisulfite treatment under non-denatured conditions in wild type alleles of FMR1, C9orf72 and RPLA13A
 
Contributor(s) Rachel E
Citation(s) 30396881
Submission date Mar 13, 2018
Last update date Jan 25, 2019
Contact name Manar Abu Diab
E-mail(s) manar@szmc.org.il
Phone 0529597400
Organization name Shaare Zedek Medical Center
Department Genetics
Lab Stem Cells
Street address Shmu'el Bait St 12, Jerusalem, 9103102
City jerusalem
ZIP/Postal code 9670406
Country Israel
 
Platforms (1)
GPL15520 Illumina MiSeq (Homo sapiens)
Samples (7)
GSM3038970 FMR1_ WT-ES-4
GSM3038971 FMR1_uFM-ES-2
GSM3038972 C9orf72_WT-ES-5
Relations
BioProject PRJNA438054
SRA SRP135232

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE111743_RAW.tar 33.7 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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