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| Status |
Public on May 01, 2018 |
| Title |
Differential expression of IBD susceptibility and IL23R associated pathway genes during ongoing anti-TNF therapy (anti-TNF non-responder vs anti-TNF responder) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
IL23R signaling dependent genes are significantly upregulated in Crohn’s disease non-responders compared to responders during ongoing anti-TNF therapy
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| Overall design |
For microarray experiments gene expression profiles of isolated LPMCs from three responders and three non-responders to anti-TNF therapy in CD patients were analyzed
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| Contributor(s) |
Schmitt H, Billmeier U, Dieterich W, Rath T, Sonnewald S, Reid S, Hirschmann S, Hildner K, Waldner MJ, Mudter J, Hartmann A, Grützmann R, Neufert C, Münster T, Neurath MF, Atreya R |
| Citation(s) |
29848778 |
| Submission date |
Mar 13, 2018 |
| Last update date |
Jul 31, 2018 |
| Contact name |
Heike Schmitt |
| E-mail(s) |
heike.schmitt@uk-erlangen.de
|
| Organization name |
University of Erlangen-Nuremberg
|
| Department |
First Department of Medicine
|
| Street address |
Ulmenweg 18
|
| City |
Erlangen |
| ZIP/Postal code |
91054 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL13497 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version) |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA438079 |
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