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Series GSE112201 Query DataSets for GSE112201
Status Public on Mar 23, 2018
Title RNA Misplicing in Fuchs Endothelial Corneal Dystrophy II
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-Seq splicing data from the corneal endothelia of FECD patients and controls reveal hundreds of differential alternative splicing events. These include events previously characterized in the context of myotonic dystrophy type 1 and epithelial-to-mesenchymal transition, as well as splicing changes in genes related to proposed mechanisms of FECD pathogenesis.
Overall design RNA-Seq was used to compare corneal endothelial specimens from subjects with Fuchs endothelial corneal dystrophy. Control samples from normal subjects were also provided.
Contributor(s) Fautsch MP, Baratz KH, Wieben ED
Citation(s) 29966009, 31469403, 28118661
Submission date Mar 22, 2018
Last update date Nov 24, 2020
Contact name Xiaojia Tang
Organization name Mayo Clinic
Street address 200 1st ST SW
City Rochester
State/province MN
ZIP/Postal code 55905
Country USA
Platforms (2)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (28)
GSM3060909 2011-024 RNA16
GSM3060910 2011-041 RNA15
GSM3060911 6004 RNA19
BioProject PRJNA445238
SRA SRP136239

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE112201_GeneCounts.tsv.gz 1.3 Mb (ftp)(http) TSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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