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Series GSE112365 Query DataSets for GSE112365
Status Public on Mar 28, 2018
Title A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Deficiency of deacetylase SIRT1 or its downstream target PRRX1 promotes breast cancer stemness and metastasis. To explore the mechnisms of SIRT1 and its downstream target PRRX1 in breast cancer, we analysed the gene expressions in breast cancer BT549 cells with SIRT1 knockout or PRRX1 knockout or not.
 
Overall design The mRNA profiles of breast cancer BT549 cells with SIRT1 knockout or PRRX1 knocknout or not were generated by deep sequencing using Illumina HiSeq x ten
 
Contributor(s) Shi L, Liu B
Citation(s) 30038266
Submission date Mar 27, 2018
Last update date Mar 20, 2019
Contact name Xiaolong Tang
E-mail(s) terrytang15szu@163.com
Organization name shenzhen university
Street address 3688 Nanhai Ave, Nanshan District
City shenzhen
ZIP/Postal code 518060
Country China
 
Platforms (1)
GPL20795 HiSeq X Ten (Homo sapiens)
Samples (9)
GSM3068400 WT-rep1
GSM3068401 WT-rep2
GSM3068402 WT-rep3
Relations
BioProject PRJNA445823
SRA SRP136531

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE112365_all_samples_rpkm_and_RC.txt.gz 1.0 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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