|
| Status |
Public on Oct 18, 2018 |
| Title |
RNA-sequencing to investigate transcriptional changes caused by ZNF384 fusion proteins in murine pre-B cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-sequencing was performed on Arf-/- pre-B cell expressing either wild-type ZNF384, TAF15-ZNF384, or TCF3-ZNF384. We found that pre-B cells that express ZNF384 fusion proteins have a gene expression profile similar to patients with ZNF384-rearranged leukemia.
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| |
|
| Overall design |
2 biological replicates of 3 genetically-modified cells lines
|
| |
|
| Contributor(s) |
Mullighan CG, Dickerson KM, Xu B |
| Citation(s) |
30209392 |
| Submission date |
Mar 30, 2018 |
| Last update date |
Mar 08, 2019 |
| Contact name |
Beisi Xu |
| E-mail(s) |
beisi.xu@stjude.org
|
| Organization name |
St Jude Children's Research Hosipital
|
| Department |
Center for Applied Bioinformatics
|
| Street address |
262 Danny Thomas Pl
|
| City |
Memphis |
| State/province |
Tennessee |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE112561 |
Genomic classification and identification of the cell of origin of pediatric mixed phenotype acute leukemia |
|
| Relations |
| BioProject |
PRJNA448177 |
| SRA |
SRP136838 |
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