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Series GSE112827 Query DataSets for GSE112827
Status Public on Apr 11, 2019
Title Impact of Dnm3os silencing on bleomycin-induced lung fibrosis
Organism Mus musculus
Experiment type Expression profiling by array
Summary To assess the impact of Dnm3os silencing on lung fibrogenesis, anti-Dnm3os gapmers (5mg/kg, 2 distinct designs: GP DNM3OS-1 and GP DNM3OS-3) or control gapmer (5mg/kg, GP Ctrl) formulated for in vivo delivery was instilled intratracheally 4 days and 2 days before intratracheal administration of bleomycin (1 unit/kg) or PBS as well as 4 days after bleomycin or PBS treatment.
 
Overall design Experiments were performed in a one color design, corresponding to 6 conditions (GP Ctrl + PBS n = 3, GP DNM3OS-1 + PBS n = 3, GP DNM3OS-3 + PBS n = 3, GP Ctrl + Bleo n = 5, GP DNM3OS-1 + Bleo n = 5, GP DNM3OS-3 + Bleo n = 5) for a total of 24 samples.
Web link http://www.genomique.info:8080/merge/index
 
Contributor(s) Savary G, Nottet N, Pottier N, Mari B, Barbry P, Lebrigand K
Citation(s) 30964696
Submission date Apr 06, 2018
Last update date Mar 31, 2020
Contact name Kevin Lebrigand
Organization name IPMC/CNRS
Lab Functional Genomics Platform of Nice-Sophia-Antipolis, France.
Street address 660 route des lucioles
City Valbonne - Sophia-Antipolis
ZIP/Postal code 06560
Country France
 
Platforms (1)
GPL13912 Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version)
Samples (24)
GSM3084517 Bleo_GP DNM3OS-1_Sample4
GSM3084518 Bleo_GP Ctrl_Sample4
GSM3084519 PBS_GP DNM3OS-3_Sample1
This SubSeries is part of SuperSeries:
GSE97834 The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis
Relations
BioProject PRJNA449099

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE112827_RAW.tar 294.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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