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| Status |
Public on May 07, 2021 |
| Title |
RNA-sequencing analysis of aberrantly expressed long non-coding RNAs and mRNAs in a mouse model of ventilator-induced lung injury |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Long non-coding RNAs are closely associated with the regulation of various biological processes and are involved in the pathogenesis of numerous diseases. However, the role of lncRNAs in ventilator-induced lung injury (VILI) has yet to be evaluated. This study aims to evaluate the expression profile and role of lncRNAs and mRNAs in VILI.
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| Overall design |
In the present study, high-throughput sequencing was applied to investigate differentially expressed lncRNAs and mRNAs (fold change >2; false discovery rate <0.05). Bioinformatics analysis was employed to predict the functions of differentially expressed lncRNAs.
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| Contributor(s) |
Xu B, Wang Y, Li X, Mao Y, Deng X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 07, 2018 |
| Last update date |
May 07, 2021 |
| Contact name |
Bo Xu |
| E-mail(s) |
xubo@xinhuamed.com.cn
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| Phone |
+8613761146277
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| Organization name |
Xinhua Hospital, Shanghai Jiaotong University, School of Medicine
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| Department |
Department of Anesthesiology and SICU
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| Street address |
1665 Kongjiang Road
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| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200092 |
| Country |
China |
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| Platforms (1) |
| GPL18635 |
Ion Torrent Proton (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA464384 |
| SRA |
SRP144777 |
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