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| Status |
Public on May 01, 2009 |
| Title |
Gene expression of osteosarcoma cell (U2OS, MG63) lines relative to normal human osteoblasts (HOB) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions.
Cancer-specific changes in gene expression play an essential role in cancer occurrence, and ultimately lead to cancer-related self-sufficiency in growth signals, insensitivity to growth inhibitory signals, evasion of apoptosis, limitless replicative potential, angiogenesis, and metastasis. We aimed to analyse such changes in gene expression related to osteosarcoma.
Keywords: Comparative
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| |
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| Overall design |
We performed genome-wide comparison of gene expression and identified genes that are differentialy expressed in osteosarcoma (U2OS, MG63) cell lines relative to normal human osteoblasts (HOB)
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| |
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| Contributor(s) |
Sadikovic B |
| Citation(s) |
18698372 |
| Submission date |
May 12, 2008 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Bekim Sadikovic |
| E-mail(s) |
bsadikov@gmail.com
|
| Organization name |
The SickKids Hospital and Princess Margaret Hospital
|
| Street address |
555 University Avenue
|
| City |
Toronto |
| State/province |
Ontario |
| ZIP/Postal code |
M5G 1X8 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE11416 |
Comparison of osteosarcoma cell lines and normal human osteoblasts |
|
| Relations |
| BioProject |
PRJNA109229 |
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