|
| Status |
Public on Sep 12, 2018 |
| Title |
Effect of an Analgesic Drug on Necelus Pulposus Cells from Human Intervertebral Disc (IVD) Tissues |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Neurotropin (NTP), a non-protein extract from inflamed rabbit skin inoculated with vaccinia virus. It has been widely used in Japan to treat low back pain. The current sutudy evaluated its stimulative effect on the disc cells to enhance glycosaminoglycan synthesis, which is one of the most important functions of the cells.
Gene expression profile was exzamined in the cells treated with or without NTP in vitro.
|
| |
|
| Overall design |
Cultured human nucleus pulposus cells were treated with NTP every second day for a week. Total RNA was prepared from the harvested cells, and analyzed gene expression. RNA from the cells cultured in the basal medium for the same time period was used as control.
|
| |
|
| Contributor(s) |
Sakai D, Nakai T |
| Citation(s) |
30148873 |
| Submission date |
May 08, 2018 |
| Last update date |
Sep 12, 2018 |
| Contact name |
Tomoko Nakai |
| E-mail(s) |
retnakai@tsc.u-tokai.ac.jp
|
| Phone |
+81-463-93-1121
|
| Organization name |
Tokai University School of Medicine
|
| Department |
Orthopaedic Surgery, Surgical Science
|
| Street address |
Shimokasuya143
|
| City |
Isehara |
| State/province |
Kanagawa |
| ZIP/Postal code |
259-1193 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA467767 |
Less...
More...