|
| Status |
Public on Oct 11, 2018 |
| Title |
A slow cycling Lgr5 tumour population mediates basal cell carcinoma relapse after therapy |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We used microarray analysis to molecularly profile distinct tumour cell populations present in untreated and vismodegib-treated basal cell carcinomas.
|
| |
|
| Overall design |
We FACS-sorted the basal cell carcinoma tumour cells according to their levels of Lgr5-GFP and Lrig1 expression and we performed microarray analysis on the different FACS-sorted tumour cell populations.
|
| |
|
| Contributor(s) |
Sánchez-Danés A, Blanpain C |
| Citation(s) |
30297799 |
| Submission date |
Jul 20, 2018 |
| Last update date |
Oct 11, 2018 |
| Contact name |
Adriana Sanchez-Danes |
| E-mail(s) |
adrianasanchezdanes@yahoo.es
|
| Organization name |
Université Libre de Bruxelles
|
| Street address |
Route de Lennik 808
|
| City |
Bruxelles |
| ZIP/Postal code |
1070 |
| Country |
Belgium |
| |
|
| Platforms (1) |
| GPL11180 |
[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate |
|
| Samples (8)
|
| GSM3300785 |
Untreated mouse 1: Lrg5-Lrig1+ population |
| GSM3300786 |
Untreated mouse 1: Lgr5+Lrig1+ population |
| GSM3300787 |
Vismodegib mouse 1: Lrg5-Lrig1+ population |
| GSM3300788 |
Vismodegib mouse 1: Lgr5+Lrig1+ population |
| GSM3300789 |
Untreated mouse 2: Lrg5-Lrig1+population |
| GSM3300790 |
Untreated mouse 2: Lgr5+Lrig1+ population |
| GSM3300791 |
Vismodegib mouse 2: Lrg5-Lrig1+ population |
| GSM3300792 |
Vismodegib mouse 2: Lgr5+Lrig1+ population |
|
| Relations |
| BioProject |
PRJNA482149 |
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