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| Status |
Public on Aug 02, 2018 |
| Title |
Expression data from mouse bone marrow sinusoidal endothelial cells (SECs) before and after the ablation of classical dendrtic cells (cDCs) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The function of bone marrow sinusoidal endothelial cells may change upon the ablation of classical dendritic cells to promote vascular permeability and angiogenesis
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| Overall design |
Zbtb46dtr bone marrow were transplanted into irradiated wild-type recipients. After 8 weeks, these mice were treated with diphtheria toxin (DT) to ablate cDCs, or PBS as control. Sinusoidal endothelial cells were sorted from the bone marrow of these mice, and their RNA expression was analyzed using RNA-sequencing
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| Contributor(s) |
Zhang J, Link DC |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 01, 2018 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Daniel C Link |
| E-mail(s) |
dlink@wustl.edu
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| Phone |
314-362-8771
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| Organization name |
Washington University in St Louis
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| Department |
Internal Medicine
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| Street address |
660 South Euclid Avenue
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| City |
St. Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
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| Platforms (1) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
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| Samples (7)
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| GSM3317307 |
Bone marrow sinusoidal endothelial cells, PBS treated, biological rep 1 |
| GSM3317308 |
Bone marrow sinusoidal endothelial cells, PBS treated, biological rep 2 |
| GSM3317309 |
Bone marrow sinusoidal endothelial cells, PBS treated, biological rep 3 |
| GSM3317310 |
Bone marrow sinusoidal endothelial cells, PBS treated, biological rep 4 |
| GSM3317311 |
Bone marrow sinusoidal endothelial cells, DT treated, biological rep 1 |
| GSM3317312 |
Bone marrow sinusoidal endothelial cells, DT treated, biological rep 2 |
| GSM3317313 |
Bone marrow sinusoidal endothelial cells, DT treated, biological rep 3 |
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| Relations |
| BioProject |
PRJNA484014 |
| SRA |
SRP156050 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE118017_Normalized_count_data_FPKM.txt.gz |
760.7 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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