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| Status |
Public on May 25, 2020 |
| Title |
CCR7L-inducible lnc-Dpf3 restrains dendritic cell migration by inhibiting HIF1α-mediated glycolysis (mRNA) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Purpose: The purpose is to systemically identify RNA expression changes after lnc-Dpf3 knockdown in CCR7-stimulated mDCs
Methods: We profiled RNA seq in mDCs transfected with si-Lnc-Dpf3 or si-NC and stimulated with or without CCR7 ligand CCL19 and CCL21.
Results: CCR7 stimulation induced profound RNA expression changes in mDCs, and a set of genes were differentially expressed in lnc-Dpf3-knockdown DC
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| Overall design |
mDCs were transfected with si-Lnc-Dpf3 or si-NC and stimulated with or without CCR7 ligand CCL19 and CCL21 (CCR7L) for 12 h or left unstimulated (Med), and then subjected to RNA seq
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| Contributor(s) |
Cao X, Liu J |
| Citation(s) |
30824325 |
| Submission date |
Aug 14, 2018 |
| Last update date |
May 25, 2020 |
| Contact name |
kun chen |
| E-mail(s) |
kunc109727@163.com
|
| Phone |
+8615900809470
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| Organization name |
Zhejiang University
|
| Street address |
No.800 Xiangyin Road, Yangpu District
|
| City |
shanghai |
| ZIP/Postal code |
200433 |
| Country |
China |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA485962 |
| SRA |
SRP157908 |
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