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| Status |
Public on Aug 17, 2018 |
| Title |
Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis (jNCL) mice highly susceptible to light damage |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We compared retinal transcriptomes of jNCL mice and wild-type mice under conditions of light damage
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| |
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| Overall design |
total RNA from mouse retinas of Balb/c mice and jNCL mice under conditions of no light, high light, treatment with minocycline or solvent was analyzed using Affymetrix Clariom S (mouse) arrays. Biological duplicates were performed for each condition.
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| |
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| Contributor(s) |
Langmann T, Dannhausen K |
| Citation(s) |
30042155 |
| Submission date |
Aug 16, 2018 |
| Last update date |
Feb 01, 2019 |
| Contact name |
Thomas Langmann |
| E-mail(s) |
thomas.langmann@uk-koeln.de
|
| Organization name |
University of Cologne
|
| Department |
Department of Ophthalmology
|
| Lab |
Experimental Immunology of the Eye
|
| Street address |
Kerpener Strasse 62
|
| City |
Cologne |
| ZIP/Postal code |
50931 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA486374 |
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