|
| Status |
Public on Nov 10, 2008 |
| Title |
Illumina expression data from LNCaP cells overexpressing either SOX4 or GFP |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
SOX4 is a critical developmental transcription factor in vertebrates and is required for precise differentiation and proliferation in multiple tissues. In addition, SOX4 is overexpressed in many human malignancies, but the precise role of SOX4 in cancer progression is not well understood. Here we have performed an expression profiling experiment of LNCaP cells either overexpressing SOX4 or GFP to identify SOX4 target genes.
Keywords: Gene expression
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| |
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| Overall design |
LNCaP prostate cancer cells were transfected with either SOX4 or GFP expression vectors and total RNA harvested 24 hours post-transfection. Each transfection and RNA isolation was performed in triplicate and each hybridization was performed in duplicate providing 12 overall hybridizations on the Illumina platform.
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| |
|
| Contributor(s) |
Moreno CS, Scharer C |
| Citation(s) |
19147588 |
| Submission date |
Jun 27, 2008 |
| Last update date |
Feb 15, 2013 |
| Contact name |
Chris Scharer |
| E-mail(s) |
cdschar@emory.edu
|
| Organization name |
Emory University
|
| Department |
Microbiology and Immunology
|
| Lab |
Chris Scharer
|
| Street address |
1510 Clifton Rd, Suite 3086A
|
| City |
Atlanta |
| State/province |
GA |
| ZIP/Postal code |
30322 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6102 |
Illumina human-6 v2.0 expression beadchip |
|
| Samples (12)
|
| GSM301107 |
LNCaP SOX4 hybridization 1 Replicate 1 |
| GSM301108 |
LNCaP SOX4 hybridization 1 Replicate 2 |
| GSM301109 |
LNCaP SOX4 hybridization 1 Replicate 3 |
| GSM301110 |
LNCaP SOX4 hybridization 2 Replicate 1 |
| GSM301111 |
LNCaP SOX4 hybridization 2 Replicate 2 |
| GSM301112 |
LNCaP SOX4 hybridization 2 Replicate 3 |
| GSM301113 |
LNCaP GFP hybridization 1 Replicate 1 |
| GSM301114 |
LNCaP GFP hybridization 1 Replicate 2 |
| GSM301115 |
LNCaP GFP hybridization 1 Replicate 3 |
| GSM301116 |
LNCaP GFP hybridization 2 Replicate 1 |
| GSM301117 |
LNCaP GFP hybridization 2 Replicate 2 |
| GSM301118 |
LNCaP GFP hybridization 2 Replicate 3 |
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| This SubSeries is part of SuperSeries: |
| GSE11915 |
SOX4 effect on LNCaP prostate cancer cells |
|
| Relations |
| BioProject |
PRJNA109245 |
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