|
| Status |
Public on Sep 22, 2018 |
| Title |
Effects of LSD1 inhibitors on enhancer functions in T-ALL cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We treated the T-ALL cell line MOLT4 with a novel LSD inhibitor and performed ChIP-seq analysis using anti-histoneH3K27ac antibody to assess the enhancer function.
|
| |
|
| Overall design |
We isolated fixed chromatin from MOLT4 cells treated with the LSD1 inhibitor S2157 and performed immunoprecipitation with anti-H3K27ac antibody, followed by deep sequencing.
|
| |
|
| Contributor(s) |
Furukawa Y, Kikuchi J |
| Citation(s) |
30518632 |
| Submission date |
Sep 21, 2018 |
| Last update date |
Feb 21, 2019 |
| Contact name |
Yusuke Furukawa |
| E-mail(s) |
furuyu@jichi.ac.jp
|
| Phone |
011-81-285-58-7399
|
| Organization name |
Jichi Medical University
|
| Department |
Center for Molecular Medicine
|
| Lab |
Division of Stem Cell Regulation
|
| Street address |
3311-1 Yakushiji
|
| City |
Shimotsuke |
| State/province |
Tochigi |
| ZIP/Postal code |
329-0498 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL9052 |
Illumina Genome Analyzer (Homo sapiens) |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA492486 |
| SRA |
SRP162352 |
