|
| Status |
Public on Oct 15, 2008 |
| Title |
Expression data from Emx2 wildtype and knockout olfactory epithelium |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Emx2 is a homeobox transcription factor that plays a critical role in development. Olfactory sensory neuron axons from Emx2 knockout mice fail to innervate their target tissue, the olfactory bulb. Homeobox transcription factors may also play an important role in olfactory receptor expression.
We used microarrays to analyze differences in mRNA abundance in the olfactory epithelium of Emx2 wildtype and knockout embryonic day 18.5 mice.
Keywords: Knockout-Wildtype comparision
|
| |
|
| Overall design |
Total RNA from 9 Emx2 wildtype and 9 Emx2 knockout mice was analyzed. Equal amounts of RNA from 3 animals was pooled to create one biological sample, 3 pools per genotype, 6 chips total. RNA was hybridized to the Affymetrix Mouse Exon 1.0 ST array.
|
| |
|
| Contributor(s) |
McIntyre JC, McClintock TS |
| Citation(s) |
18854508 |
| Submission date |
Jul 16, 2008 |
| Last update date |
Mar 06, 2018 |
| Contact name |
Jeremy C McIntyre |
| E-mail(s) |
jmcin2@uky.edu
|
| Phone |
859-323-1084
|
| Organization name |
University of Kentucky
|
| Department |
Physiology
|
| Street address |
800 Rose St
|
| City |
Lexington |
| State/province |
KY |
| ZIP/Postal code |
40536 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6096 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
|
| GSM305873 |
Olfactory Epithelium-Emx2 Wildtype_replicate 1 |
| GSM305874 |
Olfactory Epithelium-Emx2 Wildtype_replicate 2 |
| GSM305875 |
Olfactory Epithelium-Emx2 Wildtype_replicate 3 |
| GSM305876 |
Olfactory Epithlium-Emx2 Knockout-replicate 1 |
| GSM305877 |
Olfactory Epithlium-Emx2 Knockout-replicate 2 |
| GSM305878 |
Olfactory Epithlium-Emx2 Knockout-replicate 3 |
|
| Relations |
| BioProject |
PRJNA113501 |
Less...
More...