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| Status |
Public on Oct 19, 2018 |
| Title |
Expression profiles in circRHOT1-deficient or control HCC cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNA-sequencing of Human hepatocellular carcinoma (HCC) cells
We analyzed two circRNA profiles expressed in human HCC tissues and identified circRHOT1 as a conserved and dramatically upregulated circRNA in HCC tissues. HCC patients displaying high circRHOT1 level possessed poor prognosis. We demonstrated circRHOT1 significantly promoted HCC growth and metastasis. In order to investigate the mechansim of circRHOT1, we constructed circRHOT1-deficient HCC cell lines. Through RNA-sequencing, we sough to identify the key gene regulated by circRHOT1 in HCC.
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| Overall design |
two circRNA profiles expressed in human HCC tissues
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| Contributor(s) |
Li B, Wang L |
| Citation missing |
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| BioProject |
PRJNA496386 |
| Submission date |
Oct 18, 2018 |
| Last update date |
Jan 07, 2019 |
| Contact name |
b Li |
| E-mail(s) |
binli_01@163.com
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| Organization name |
Affiliated Hospital of Guilin Medical University
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| Department |
Gastrointestinal Department
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| Street address |
Lequn road No.15
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| City |
Guilin |
| ZIP/Postal code |
541001 |
| Country |
China |
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| Platforms (1) |
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| Samples (2) |
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| Relations |
| SRA |
SRP165820 |
