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| Status |
Public on Nov 18, 2018 |
| Title |
Impact of CD22 CAR T-cell therapy on leukemia cell transcriptome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Although CD19 CAR T therapy has attained encouraging clinical outcomes worldwide, leukemia relapse after this therapy is associated with particular poor prognosis and has become an urgent problem to be solved. In consideration of the possible genetic or transcriptomic mechanisms underlying relapse, leukemia samples before CAR T cell infusion and after relapse were subjected to transcriptome sequencing
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| |
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| Overall design |
Two B-ALL samples from the same patient, collected respectively at his pre-treatment stage and after the tumor relapse
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| |
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| Contributor(s) |
Pan J, Niu Q, Feng X, Tong C |
| Citation(s) |
31110217 |
| Submission date |
Nov 17, 2018 |
| Last update date |
May 24, 2019 |
| Contact name |
Qing Niu |
| E-mail(s) |
gloomydream@live.cn
|
| Organization name |
Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College
|
| Street address |
No. 288, Nanjing Road, Heping District
|
| City |
Tianjin |
| ZIP/Postal code |
300020 |
| Country |
China |
| |
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| Platforms (1) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA505889 |
| SRA |
SRP169506 |
