|
| Status |
Public on Apr 17, 2019 |
| Title |
Oct1/Pou2f1 is selectively required for gut regeneration and regulates gut malignancy |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
As part of a larger study focused on deletion of Oct1 (Pou2f1) in the mouse gut, we identify Oct1 target genes in HCT116 colon carcinomal cells, with H3K4me3 and input controls. Identified target genes are associated with mitotic stability, metabolism, stress response and malignancy.
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| |
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| Overall design |
Oct1- or H3K4me3-enriched DNA fragments, and input controls, were sequenced in triplicate
|
| |
|
| Contributor(s) |
Vázquez-Arreguín K, Tantin D |
| Citation(s) |
31059499 |
| Submission date |
Dec 07, 2018 |
| Last update date |
May 07, 2019 |
| Contact name |
Dean Tantin |
| E-mail(s) |
dean.tantin@path.utah.edu
|
| Phone |
(801) 587-3035
|
| Organization name |
University of Utah
|
| Department |
Department of Pathology
|
| Street address |
15 North Medical Drive East
|
| City |
Salt Lake City |
| State/province |
UT |
| ZIP/Postal code |
84112 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA509072 |
| SRA |
SRP173207 |
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