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Series GSE123540 Query DataSets for GSE123540
Status Public on Dec 11, 2018
Title Expression data from mouse skeletal muscle
Organism Mus musculus
Experiment type Expression profiling by array
Summary Evidence suggests that diabetes mellitus is a promoting factor of sarcopenia; mechanism of how diabetes mellitus accelerates the development of sarcopenia is not known. We have recently established a model of diabetes-induced skeletal muscle mass loss in mice by using streptozotocin.
We used microarrays to detail the global programme of gene expression underlying skeletal muscle atrophy in STZ treated mice and identified up-regulated or down-regulated genes during this process.
 
Overall design Gastrocnemius muscle were selected at 3 weeks after STZ treatment of wild type or skeletal muscle specific KLF15 knockout mice for RNA extraction and hybridization on Affymetrix microarrays.
 
Contributor(s) Hirata Y, Ogawa W
Citation(s) 30830866
Submission date Dec 10, 2018
Last update date Mar 12, 2019
Contact name Yu Hirata
E-mail(s) yuhirata@med.kobe-u.ac.jp
Organization name Kobe University
Street address chuo-ku, kusunoki-chou, 7-5-2
City kobe
ZIP/Postal code 650-0017
Country Japan
 
Platforms (1)
GPL16570 [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version]
Samples (4)
GSM3506295 WT, Control
GSM3506296 WT, STZ
GSM3506297 KO, Control
Relations
BioProject PRJNA509152

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE123540_RAW.tar 30.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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