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| Status |
Public on Dec 20, 2018 |
| Title |
Expression Profile of Genes in Trabecular Meshwork Cells Treated with Dexamethasone |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Treatment with glucocorticoids is known to cause ocular hypertension in humans which can lead to steriod-induced glaucoma
We used microarrays to determine changes in gene expression in two human trabecular meshwork (TM) cell isolates (TM-4 and TM-2) from the same donor that could explain the increase in ocular hypertension.
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| |
|
| Overall design |
RNA was extracted from confluent cultures of trabecular meshwork cells treated with and without dexamethasone (DEX) for 6 days and prepared for hybridization on Affymetrix microarrays
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| |
|
| Contributor(s) |
Peters DM |
| Citation(s) |
31516309 |
| Submission date |
Dec 19, 2018 |
| Last update date |
Sep 18, 2019 |
| Contact name |
Donna Peters |
| E-mail(s) |
dmpeter2@wisc.edu
|
| Phone |
608-262-4626
|
| Organization name |
UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE
|
| Department |
Pathology & Laboratory Medicine
|
| Street address |
1300 UNIVERSITY AVE
|
| City |
MADISON |
| State/province |
WI- WISCONSIN |
| ZIP/Postal code |
53706 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (18)
|
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| Relations |
| BioProject |
PRJNA510794 |
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