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Series GSE125179 Query DataSets for GSE125179
Status Public on May 15, 2019
Title microRNA modulated networks of adaptive and innate immune response in pancreatic ductal adenocarcinoma
Platform organism synthetic construct
Sample organism Homo sapiens
Experiment type Non-coding RNA profiling by array
Summary Despite progress in treatment strategies, only ~24% of pancreatic ductal adenocarcinoma (PDAC) patients survive >1 year. Our goal was to elucidate deregulated pathways modulated by microRNAs (miRNAs) in PDAC and Vater ampulla (AMP) cancers.
 
Overall design Global miRNA expression was identified in 19 PDAC, 6 AMP and 25 paired, histologically normal pancreatic tissues using the GeneChip® 4.0 miRNA arrays. Computational approaches were used for miRNA target prediction/identification of miRNA-regulated pathways.
 
Contributor(s) Felix TF, Lopez Lapa RM, de Carvalho M, Bertoni N, Tokar T, Oliveira RA, Rodrigues MA, Hasimoto CN, Oliveira WK, Pelafsky L, Spadella CT, Llanos JC, Silva GF, Lam WL, Regina Rogatto S, Schultz Amorim L, Drigo SA, Carvalho RF, Reis PP
Citation(s) 31150430
Submission date Jan 16, 2019
Last update date Jun 24, 2019
Contact name Tainara Francini Felix
E-mail(s) felix.tainara@gmail.com
Phone 14996257103
Organization name UNESP
Department Surgery and Orthopedics
Street address Av. Prof. Mário Rubens Guimarães Montenegro, s/n, s/n
City Botucatu
State/province SP
ZIP/Postal code 18618-687
Country Brazil
 
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (28)
GSM3564672 PDAC1: Pancreatic ductal adenocarcinoma 01
GSM3564673 PDAC2: Pancreatic ductal adenocarcinoma 02
GSM3564674 PDAC3: Pancreatic ductal adenocarcinoma 03
Relations
BioProject PRJNA515480

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE125179_RAW.tar 21.8 Mb (http)(custom) TAR (of CEL, CHP)
Processed data provided as supplementary file
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