|
| Status |
Public on Oct 01, 2010 |
| Title |
Profiling of novel p53-inducing compounds |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We describe six novel lead compounds activating the p53 tumor suppressor pathway. Transcriptional profiling indicated that they invoked highly similar responses involving p53 and cell cycle pathways and DNA damage response signaling.
Keywords: Stress response
|
| |
|
| Overall design |
Six compounds and one vehicle control, with four biological replicates each, for a total of 28 samples.
|
| |
|
| Contributor(s) |
Liu HH, Laiho M |
| Citation missing |
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| Submission date |
Sep 04, 2008 |
| Last update date |
Dec 06, 2018 |
| Contact name |
hester liu |
| E-mail(s) |
hester@jhmi.edu
|
| Phone |
443-287-0077
|
| Organization name |
Johns Hopkins University
|
| Department |
Radiation Oncology
|
| Lab |
MRS
|
| Street address |
1550 Orleans st
|
| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21231 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
|
| Samples (28)
|
|
| Relations |
| BioProject |
PRJNA112735 |
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