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Series GSE126743 Query DataSets for GSE126743
Status Public on Oct 02, 2020
Title Genome-wide maps of chromatin state in TRIB3-shRNA and control lymphoma cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We report the application of single-molecule-based sequencing technology for high-throughput profiling of RNAPII with promoters in mammalian cells. We performed ChIP sequencing with antibody to total RNAPII in TRIB3-cas9 and control group. Inspection of multiple individual traces and global analyses showed that TRIB3 deletion globally reduced association of RNAPII with promoters.
 
Overall design we performed ChIP sequencing with antibody to total RNAPII in TRIB3 deleted group. Inspection of individual traces and global analyses showed that TRIB3 deletion globally reduced association of RNAPII with promoters.
 
Contributor(s) Hu Z, Li K, Wang F
Citation(s) 33298911
Submission date Feb 19, 2019
Last update date Dec 22, 2020
Contact name wang feng
E-mail(s) wangfeng123@imm.ac.cn
Phone 15624968856
Organization name Chinese Academy of Medical Sciences & Peking Union Medical College,
Street address nan wei road
City bei jing
ZIP/Postal code associate professor
Country China
 
Platforms (1)
GPL20795 HiSeq X Ten (Homo sapiens)
Samples (4)
GSM3612047 Ip-c-RNAPII_ChIPSeq
GSM3612048 Ip-TRIB3-cas9-RNAPII_ChIPSeq
GSM3612049 Input-c-RNAPII_ChIPSeq
This SubSeries is part of SuperSeries:
GSE126258 TRIB3 Promotes C-Myc-Associated Lymphomagenesis through Inhibition of UBE3B-Mediated c-Myc Degradation
Relations
BioProject PRJNA523177
SRA SRP186263

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE126743_RAW.tar 593.5 Mb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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