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| Status |
Public on Sep 05, 2009 |
| Title |
Hypoxia effect on embryonic hearts of Tibetan Chicken, Dwarf Recessive White Chicken and Shouguang Chicken |
| Organism |
Gallus gallus |
| Experiment type |
Expression profiling by array
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| Summary |
Adaptation to hypoxia is a complicated and important physiological course for organisms, but the genetic mechanism underlying the adaptation is not fully understood yet. Tibetan Chicken (T), an indigenous chicken breed in China which inhabit in high areas with an altitude above 2,900 meters. Shouguang Chicken(S) and Dwarf Recessive White Chicken (DRW), two lowland chicken breeds, were used as control groups. The heart was the first functional organ to develop during the embryonic development. Furthermore, the heart is an efficient energy converter utilizing the most appropriate fuel for a given environment. Therefore, GeneChip® Chicken Genome Array was employed to identify the differentially expressed genes in embryonic hearts of Tibetan Chicken and two lowland chicken breeds in both hypoxic and normoxic incubating environments with a genome wide profile.
Keywords: stress response
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| Overall design |
To obtain general expression profiles of embryonic hearts in Tibetan Chicken(T), Dwarf Recessive White Chicken (DRW)and Shouguang Chicken (S)in hypoxia and normoxia, the fertilized full sib eggs of all the three chicken breeds were incubated under two different conditions. The heart was isolated from all the three chicken breeds under the two different conditions for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Wu CH, Zhao CH, Li M |
| Citation(s) |
19294354 |
| Submission date |
Sep 05, 2008 |
| Last update date |
Mar 20, 2012 |
| Contact name |
mei li |
| E-mail(s) |
meili.emily@gmail.com
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| Organization name |
China Agricultural University
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| Street address |
Haidian district
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| City |
Beijing |
| ZIP/Postal code |
86100193 |
| Country |
China |
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| Platforms (1) |
| GPL3213 |
[Chicken] Affymetrix Chicken Genome Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA112749 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE12675_RAW.tar |
43.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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